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    GlossaryOrgan Size Control

    biological processes regulate growth and final size of organs

    Organ Size Control refers to the biological processes that regulate the growth and final size of organs in an organism. This involves a complex interplay of genetic, molecular, and environmental factors that ensure organs grow to the appropriate size for proper function. For example, in hair follicles, organ size control mechanisms ensure that hair grows to a specific length and thickness, which can be disrupted in conditions like alopecia.

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      learn Rapamycin

      mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

      learn Melatonin

      hormone commonly taken for sleep aid has some topical benefits for hair

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      community Verteporfin and Microneedling

      in Treatments 3 months ago
      Clinical studies by Dr. Barghouthi and Dr. Bloxham indicate that Verteporfin, when used with FUE and FUT hair transplantation methods, shows promise in hair follicle regeneration and minimal scarring due to its ability to inhibit Yes-associated protein (YAP). Microneedling at depths of 3-3.5mm, combined with Verteporfin, could potentially reactivate dormant follicles, although the optimal dosage and application method are still under investigation. Concerns remain about the DHT sensitivity of regenerated follicles, highlighting the need for further research to optimize trauma levels and Verteporfin concentrations to achieve effective and scar-free hair regeneration.

      community How is it that golden era bodybuilders kept their hair while blasting gear while in the modern era most are bald? I’m convinced there’s something in our food and water causing MPB to speed up

      in Satire  728 upvotes 1 year ago
      The conversation is about the difference in hair loss between bodybuilders in the "Golden Era" and modern bodybuilders. Some users speculate that factors such as the types and doses of steroids used, genetics, diet, microplastics, and overall health may contribute to hair loss. Hair loss prevention medication and transplants are mentioned as potential treatments.
      Diffuse hair loss and scalp biopsies

      community Diffuse hair loss and scalp biopsies

      in Research  692 upvotes 1 month ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community My hair after 3 steroid cycles

      in Progress Pictures  24 upvotes 3 months ago
      A user shared their hair progress after three steroid cycles, using 5% minoxidil and 100mg RU58841 daily. They are considering a hair transplant due to paranoia about shedding.