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Glossary Organ Regeneration

process of naturally repairing or regrowing damaged organs

Organ regeneration refers to the process by which damaged or lost organs are naturally repaired or regrown by the body. This involves the activation of stem cells and other cellular mechanisms to replace the missing tissues, restoring the organ's original structure and function. In humans, this capability is limited, but research in regenerative medicine aims to harness and enhance these processes for therapeutic purposes.

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Research

5 / 1000+ results

research Nerve dependence in tissue, organ, and appendage regeneration

228 citations , September 2012 in “Trends in Neurosciences”

This review examines the role of nerves in regeneration across various species and discusses their importance as components in the progenitor cell niche, reporting no new clinical results.

research Macrophages and fibroblasts during inflammation and tissue repair in models of organ regeneration

201 citations , April 2017 in “Regeneration”

This review examines the roles of macrophages and fibroblastic cells in organ injury and repair, discussing their impact on outcomes ranging from regeneration to fibrosis, without presenting new clinical results.

research Skin and hair: models for exploring organ regeneration

35 citations , April 2008 in “Human Molecular Genetics”

This review discusses advances in using molecular tools from skin biology to manipulate adult stem cells for regenerative medicine and reports no new clinical results.

research Organ regeneration based on developmental biology: past and future

21 citations , June 2018 in “Current Opinion in Genetics & Development”

This review discusses recent advancements in regenerative medicine, including functional organ regeneration and the creation of mini-organs, and reports no new clinical results.

research The global regulatory logic of organ regeneration: circuitry lessons from skin and its appendages

9 citations , June 2021 in “Biological reviews/Biological reviews of the Cambridge Philosophical Society”

This review discusses molecular regulatory circuitry in organ regeneration, using skin regeneration examples, and reports no new experimental results; the authors propose that understanding this circuitry might aid in developing therapeutic strategies.

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Community Join

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community Table of the relationship between physical exercise and the regeneration of the deminiaturized hair follicle

45 upvotes 1 year ago

Exercise, especially leg workouts, combined with finasteride and minoxidil, may enhance hair regrowth. Cold exposure, like cold showers, might further boost results.

community Weed/THC effects on hair growth/hair loss, and vitality of organ-culture human follicle studies (research review)

4 upvotes 1 year ago

Cannabis and THC may have mixed effects on hair, with some studies suggesting potential negative impacts on hair growth in isolated hair follicles, but these results are hard to apply to living humans. Treatments like minoxidil and finasteride are commonly used for hair loss, and the effects of cannabis might be neutral or vary based on individual factors.

community Researchers working on ways to regenerate lost hair from stem cells identified a recipe for normal hair regeneration in the lab. “A method for cyclical regeneration of hair follicles from hair follicle stem cells and will help make hair follicle regeneration therapy a reality in the near future.”

263 upvotes 5 years ago

Hair loss treatments like finasteride, minoxidil, and hair transplants have side effects and limitations. There is hope for future advancements in stem cell therapy and hair follicle regeneration, though skepticism about their effectiveness and timeline persists.

community Update and new paper from Dr tsuji

26 upvotes 7 years ago

Hair follicle regenerative therapy is being developed, with clinical trials planned in Japan, potentially allowing for hair cloning and eliminating the need for treatments like finasteride. If successful, the treatment could be available in Japan by 2025, but widespread access and affordability may take longer.

community Any updates on verteporfin? Or when should we expect an update?

5 upvotes 10 months ago

Verteporfin is discussed as a potential treatment for hair regrowth, but skepticism exists about its effectiveness in regenerating extracted hair follicles. The conversation also mentions the possibility of needing a hair transplant by 2028.

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Clinics

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Learn

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learn Rapamycin

mTOR regulator and immunosuppressant used more recently for anti-aging and hair regrowth

learn Beta Polypeptide

learn Epidermal Growth Factor

learn Stem Cell Factor

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