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In this study, a case of a 20-year-old woman revealed ectopic acanthosis nigricans at a post-syndactyly-release surgical site, suggesting this rare condition could result from epidermal–dermal mismatch and altered growth factor signaling in grafted skin, without indicating any metabolic or malignancy concerns.

This article reports on a rare case of hair yellowing induced by topical minoxidil use and discusses drug-induced hair color changes.

This study found that pigmentation following sclerotherapy is likely caused by hemosiderin deposition from red blood cells rather than post-inflammatory hyperpigmentation, with most cases resolving spontaneously within 6–24 months.

This article describes a case of oral pigmentation that posed a diagnostic challenge in determining Addison’s disease and includes a brief review, reporting no new clinical results.

This study observed that smeathxanthone A improved wound healing and reduced blood glucose levels in diabetic mice, suggesting potential benefits for tissue healing.

Vitamin B12 deficiency can cause skin darkening and increased blood vessels, but treatment can improve symptoms.

This study observed that acanthosis nigricans is highly prevalent in Latin American youths, especially at the knuckles, and may indicate early insulin resistance even in those with a normal BMI.

This study found that exogenous ochronosis from hydroquinone use in melasma treatment has distinctive dermatoscopic features that may aid in diagnosis without needing a biopsy.

This study investigated the pigments and cells causing discoloration in stasis dermatitis but did not clarify the role of melanin or melanocytes in this condition.

This case report describes a 68-year-old woman with benign mucous membrane pemphigoid and unusual keratotic plaques on her extremities, associated with longstanding mouth and eye symptoms and phalangeal swelling.

Two patients had a rare combination of red skin spots and white scaly skin lesions not on the genitals.

This case report details a Taiwanese woman with scleredema adultorum and diabetes mellitus experiencing loss of eccrine glands, which led to frequent heat strokes and anhidrosis despite treatment.

This study found that patients with hypothyroidism at a tertiary hospital in South India most commonly exhibited skin dryness (xerosis/ichthyosis) and swelling of the feet (pedal oedema).

This case report highlights an atypical presentation of vitamin B12 deficiency in a 28-year-old man with reversible symptoms including localized hand hyperpigmentation and megaloblastic anemia, resolved after B12 supplementation.

This case report describes the first instance of facial and oral mucosal hyperpigmentation and acanthosis nigricans linked to testosterone therapy in a patient with idiopathic hypogonadotropic hypogonadism.

Long-term use of canthaxanthin may cause reversible changes in the eye, including crystal deposits and altered vision responses.

This case study describes a 45-year-old male with black hairy tongue who experienced complete resolution of tongue discoloration and improved halitosis after receiving treatment focused on enhanced oral hygiene, tongue brushing, and smoking cessation.

This report describes a case of trichodysplasia spinulosa in a renal transplant patient, characterized by unique dermatoscopic features and highlighting the need for timely diagnosis.

The man has a disease causing skin patches, thickened nerves, and mild muscle weakness.

This case study of a 45-year-old man from Tonga describes the identification of pachyonychia congenita through genetic testing, revealing a mutation in the keratin gene KRT16, associated with chronic painful skin and nail conditions.

This report describes a rare case of Trichostasis Spinulosa on the heel, an uncommon location for this type of lesion.

A man with Klinefelter syndrome had a leg ulcer that didn't heal well, even with treatment.

This case report describes the diagnosis of pseudoporphyria in a hemodialysis patient, highlighting the importance of discontinuing causative medications and advising patients on sun protection to manage this photosensitive condition.

This case report describes oleoma on the thighs and buttocks appearing two years after an injection for cellulite treatment, suggesting the need for more research to ensure the procedure's safety and efficacy.

This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.

This diagnostic case study describes a 25-year-old man with oral ulcers, body rash, and erythematous nodules.

In this case study, nail changes and skin lesions helped diagnose a 60-year-old man with advanced cardiac amyloidosis, highlighting the importance of considering amyloidosis in differential diagnoses for similar nail abnormalities and assessing for systemic involvement.

This case study reports a new variant of chronic dermatophytosis with giant cutaneous horns, suggesting a possible genetic link and highlighting successful treatment with antifungal medications.

This case report describes koebnerization-induced vitiligo in a woman following repeated eyebrow microblading, suggesting a link between the procedure and the phenomenon in susceptible individuals.

This case study reports a patient with Rothmund-Thomson type congenital poikiloderma, showing primarily skin changes and hair loss, along with slightly elevated lysine and cystine levels in urine.