Segmental Cherry Angiomas Associated with Extragenital Lichen Sclerosus: A Report of Two Cases

The document reports two cases of segmental cherry angiomas associated with extragenital lichen sclerosus, which is a novel observation. Cherry angiomas, or Campbell de Morgan spots, are common small red skin papules with dilated capillary loops that usually arise spontaneously. Extragenital lichen sclerosus presents as porcelain-white scaly atrophic lesions and can occur with or without genital involvement. The two unrelated female patients, aged 46 and 66, presented with pruritic white scaly atrophic lesions in their axillae and lower abdomen, and upon examination, they also had several hundred small red skin papules in a segmental distribution. Biopsies confirmed the diagnosis of extragenital lichen sclerosus, and the papules were clinically and histologically consistent with cherry angiomas. The segmental distribution of the cherry angiomas may be due to genetic mosaicism, and while a causal link between the angiomas and lichen sclerosus is uncertain, there is a suggestion of an association with conditions that involve abnormalities of the cutaneous microcirculation, such as scleroderma. No commercial support was identified for this study.