387 citations
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May 2019 in “International Journal of Molecular Sciences” This review discusses the therapeutic potential of adipose-derived stem cells compared to other mesenchymal stem cells, emphasizing their promise in treating neurodegenerative, cardiovascular, and autoimmune diseases, but reports no new clinical results.
280 citations
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May 2005 in “Andrology” This document outlines recommendations from an international panel on testosterone therapy for aging men with late-onset hypogonadism, emphasizing the need for careful assessment and monitoring due to limited long-term safety data.
269 citations
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October 2018 in “International journal of biological macromolecules” This review discusses the cosmetic and nutricosmetic efficacy of hyaluronic acid for skin rejuvenation and reports that HA formulations show remarkable anti-aging properties.
143 citations
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January 2007 in “The American Journal of Human Genetics” This study identified four genetic loci on chromosomes 6, 10, 16, and 18 that may contribute to susceptibility for alopecia areata and suggested shared genetic factors with psoriasis.
129 citations
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February 2006 in “Andrology” This article reviews considerations and guidelines for testosterone therapy in older men with low testosterone levels but does not provide new clinical results, emphasizing the need for ongoing evaluation and careful management, particularly regarding risks related to prostate and cardiovascular health.
129 citations
,
July 2019 in “Stem Cell Research & Therapy” This review examines the role of epidermal stem cells in wound healing, discussing their characteristics and mechanisms, but does not report new clinical results.
112 citations
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August 2012 in “The American Journal of Human Genetics” In this study, two unique mutations in the RBPJ gene were identified and linked to Adams-Oliver syndrome, confirming impaired DNA binding of mutated RBPJ as a factor in this rare genetic disorder.
45 citations
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August 2023 in “Trends in Cell Biology” This review highlights the potential of in vivo reprogramming using OSKM transcription factors for developing rejuvenating and regenerative strategies, while noting the associated risk of tumorigenicity and discussing how improved understanding could lead to safer applications.
31 citations
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September 2020 in “Stem Cell Research & Therapy” Hair follicle stem cells may help repair the brain after a stroke.
16 citations
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August 2023 in “JAAD Case Reports” This review discusses the unclear etiology and potential contributing factors of frontal fibrosing alopecia and reports no new clinical findings.
12 citations
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June 2025 in “Gut Microbes” This study developed BroadAMP-GPT, a computational-experimental framework, to discover new antimicrobial peptides, identifying candidates effective against multidrug-resistant pathogens. Notably, AMP_S13 showed strong stability, low toxicity, and efficacy in infection models, highlighting the platform's potential in combating antimicrobial resistance.
9 citations
,
August 2024 in “Frontiers in Pharmacology” This review evaluates the potential of natural products and medicinal plants for myocardial infarction treatment, highlighting their therapeutic promise and mechanisms such as reducing oxidative stress and inflammation, but reports no new clinical results.
6 citations
,
January 2024 in “Journal of Cosmetic Dermatology” Alopecia areata patients have worse quality of life, anxiety, and depression than vitiligo patients.
5 citations
,
May 2024 in “Molecules” This study found that glycyrrhetinic acid, derived from licorice, may help alleviate acne symptoms by regulating lipid synthesis and inflammatory responses through multiple pathways, as observed in both in vitro and in vivo settings.
5 citations
,
January 2024 in “Science Advances” In this study, researchers identified Tenascin-C as a marker for touch dome keratinocytes, which maintain themselves and can develop into Merkel cells following injury, showing they share molecular traits with various epidermal keratinocytes.
4 citations
,
December 2022 in “International Journal of Molecular Sciences” This review discusses the role of zinc and its transporters in skin health and disorders, providing an overview without presenting new clinical results.
3 citations
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July 2022 in “Indian journal of dermatology, venereology, and leprology” This study found that patients with alopecia areata had higher levels of oxidative stress markers and lower antioxidant enzyme activity compared to healthy controls.
3 citations
,
April 2019 in “Journal of Mind and Medical Sciences” This review discusses the application of photodynamic therapy for treating oral lichen planus and indicates its potential benefits, but it reports no new clinical results.
2 citations
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March 2025 in “Quantitative Imaging in Medicine and Surgery” In this study, patients with alopecia areata showed altered hypothalamic activity and connectivity, which may be linked to the neurophysiological basis of psychological stress experienced by these patients, as assessed by functional MRI and correlated with neuropsychological evaluations.
1 citations
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February 2024 in “Environmental health perspectives” In this study, higher concentrations of environmental metals, particularly manganese, were linked to worse self-reported attention-related behaviors in adolescents from Italy, with no significant modification of this effect by iron status.
1 citations
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April 2022 in “Frontiers in Bioengineering and Biotechnology” This study found that mouse astrocytes formed cell spheres on agarose surfaces, acquired stem cell-like features, and their derived stem cells effectively differentiated into neurons that helped regenerate damaged nerves.
June 2026 in “Journal of Cosmetic Dermatology” In this study, digital treatment for androgenetic alopecia over six months led to significant improvements in quality of life among Brazilian men, particularly for those with consistent program adherence, although the absence of an in-person comparator limits causal conclusions.
This study evaluated AI chatbots' responses to scabies-related questions, finding DeepSeek had the highest accuracy despite higher hallucination rates, while ChatGPT-5.2 provided more readable and reliable information, highlighting variability and the need for cautious use of AI in health queries.
December 2025 in “Biomedicines” In this study, researchers identified two person-centered sexual function profiles among women, linked to physical and psychological factors, with PCOS showing greater, though not significant, presence in the dysfunction profile. The dysfunction was associated with higher adiposity and body-image distress.
October 2025 in “Journal of Cosmetic Dermatology” In this study, researchers found that type A botulinum toxin injections can reduce hypertrophic scars effectively, though more high-quality studies are needed to confirm the precision and stability of these therapeutic effects.
October 2025 in “Frontiers in Artificial Intelligence” This study evaluated a novel, user-friendly approach for detecting hairfall trends over time using machine learning models. The Temporal Fusion Transformer model demonstrated high accuracy in identifying anomalies in hair shedding patterns, potentially aiding in the early detection of health risks related to hormonal fluctuations.
April 2025 in “Journal of Cosmetic Dermatology” In this pilot study, the niostem device, a wearable device delivering low-level electrical stimulation, significantly increased hair density by 19.3% and thickness by 8.8% in male androgenetic alopecia patients over six months without reported adverse events.
August 2024 in “PLoS ONE” This study reported that rosemary is widely used among Jordanians for various purposes, such as improving hair condition and addressing gastrointestinal issues, with younger participants showing higher knowledge about its benefits and uses.
This study provides insights into systemic lupus erythematosus patients' experiences with Anifrolumab, highlighting improvements in symptoms and health-related quality of life, despite ongoing daily life impacts.
May 2024 in “International Journal of Nanomedicine” This review examined the diverse therapeutic potentials of cannabinoids, highlighting their applications in pain, neurological, and cancer treatments, and emphasized the benefits of biodegradable polymers in improving drug delivery; however, further clinical trials are needed to fully explore these potentials.