March 2024 in “Clinical, cosmetic and investigational dermatology” This study found that in healthy adult women, a collagen and antioxidant-rich treatment significantly improved skin elasticity, hydration, texture, and reduced wrinkles and hair fall over 56 days compared to a placebo, indicating its efficacy and safety.
July 2026 in “Archives of Dermatological Research” In this study, topical finasteride showed mild-to-moderate improvement in androgenetic alopecia among a cohort in Saudi Arabia, with combination therapy outperforming monotherapy. Adverse events were rare. The study highlights the need for prospective trials to clarify finasteride's standalone effects.
This review synthesizes current advances in transcriptomics and RNA regulatory networks, alongside stem cell-derived skin organoid research, to propose a conceptual framework for understanding and potentially guiding regenerative skin repair, without claiming clinical readiness.
March 2026 in “Journal of Cosmetic Dermatology” This review discusses platelet-rich plasma therapy for androgenic alopecia and reports no clinical results; the authors emphasize the need for standardized protocols and large-scale studies to confirm its long-term efficacy.
294 citations
,
January 2016 in “Stem Cells International” This review discusses the characteristics, biomaterials, and tissue engineering methods for adipose-derived stem cells in a 3D environment, highlighting their potential in regenerative medicine without presenting new clinical results.
143 citations
,
May 2022 in “Pharmaceuticals” This review discusses alginate-based delivery systems for probiotics, highlighting recent advances, challenges, and future directions, but reports no new clinical findings.
65 citations
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March 2022 in “Molecules” This study examines the role of nanotechnology in cosmetics, highlighting its benefits in improving ingredient solubility and stability, but also noting challenges such as cost, shelf life, and safety concerns, along with regulatory complexities, particularly in harmonizing global legislation.
44 citations
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April 2023 in “Genes & Diseases” This review discusses the paracrine function of mesenchymal stem cells in tissue regeneration and repair, focusing on secreted bioactive substances and their role under different microenvironments; it reports no new clinical results.
17 citations
,
September 2016 in “Stem cells translational medicine” In this study, using stirred-suspension bioreactors to expand dermal stem cells resulted in larger numbers, but had reduced efficiency in forming hair follicle structures compared to static culture conditions.
14 citations
,
July 2022 in “Applied Sciences” This review discusses the potential of extracellular vesicles as cell-free tools in tissue engineering and regenerative medicine, noting their emerging role in promoting tissue repair without the risk of host rejection.
12 citations
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November 2022 in “Cosmetics” This review discusses 3D printing developments in topical delivery systems, highlighting the potential for 3D printed microneedles to become prominent in personalized cosmetic applications, but reports no new experimental results.
8 citations
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March 2020 in “Colloids and surfaces. B, Biointerfaces” This study suggests that extracting hair proteins at relatively high temperatures may enhance their hemostatic properties by altering their secondary structure and increasing the precipitation of soluble fibrinogen.
2 citations
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August 2022 in “BMC veterinary research” This study confirmed the biological characteristics and multipotent differentiation potential of primary and secondary hair follicle stem cells from Arbas Cashmere goats, contributing to the understanding of adult stem cell types and characteristics.
This review highlights the potential of 3D bioprinting in developing functional, patient-specific artificial skin, addressing limitations of traditional skin grafts and advancing regenerative medicine applications.
July 2026 in “Pharmaceuticals” This review discusses the potential of marine-derived polysaccharide nanofibers as advanced wound dressings, highlighting their regenerative advantages in addressing inflammation, oxidative stress, and other healing barriers. However, it notes that clinical translation is limited by challenges in standardization, evidence, safety, and production scalability.
November 2025 in “Scientia Pharmaceutica” This review highlights that injectable biostimulatory agents like poly-L-lactic acid, polycaprolactone, and calcium hydroxyapatite are effective in regenerative aesthetics by enhancing collagen production, stimulating adipogenesis, and improving dermal quality, although further research is needed to standardize protocols and confirm long-term safety and efficacy.
10 citations
,
June 2019 in “Journal of the European Academy of Dermatology and Venereology” This article discusses the updated European Training Requirements for the specialty of Dermatology and Venereology, emphasizing the harmonization of curriculum to improve specialist training across Europe, and reports no new clinical results.
365 citations
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March 2021 in “Frontiers in Bioengineering and Biotechnology” This review discusses the potential of nanocarriers to enhance transdermal drug delivery and the combination of these carriers with physical methods, but it reports no new experimental results.
84 citations
,
June 2024 in “BMC Public Health” This study observed that while TikTok offers the best flow for videos on laryngeal cancer, YouTube provides higher quality, but video quality overall needs professional enhancement and platform algorithm improvements.
51 citations
,
April 2021 in “JAMA network open” This study found that artificial intelligence assistance improved diagnostic accuracy in dermatologic cases for primary care physicians and nurse practitioners, with higher agreement rates with reference diagnoses observed.
45 citations
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January 2013 in “Dermatology Research and Practice” This study found that patients with alopecia areata experience significantly poorer quality of life compared to the general population, affecting mental health, social functioning, and overall health outcomes.
30 citations
,
September 2020 in “Journal of Patient-Reported Outcomes” This study found that alopecia areata significantly impacts emotional and psychological well-being, relationships, and lifestyles, highlighting the need for increased awareness and effective treatments.
20 citations
,
October 2024 in “British Journal of Dermatology” In this updated guideline, the British Association of Dermatologists' expert group provided 49 management recommendations for alopecia areata and highlighted future research priorities, aiming to improve care for individuals affected by this condition.
19 citations
,
October 2021 in “Medicine” In this study, anemia was commonly observed in exercising women, especially those with heavy menstrual bleeding, and the authors recommend using a simple screening tool involving haemoglobin testing.
18 citations
,
May 2023 in “Preprints.org” This review provides an overview of caffeine's effects on cancer, cardiovascular, immunological, inflammatory, and neurological diseases, highlighting both its potential benefits, such as neuroprotection and anti-aging, and possible adverse effects like elevated blood pressure, anemia, and migraine.
15 citations
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March 2023 in “Heliyon” This study found that water-soluble beehive extract exhibited anxiolytic, antidepressant, and anti-inflammatory effects in animal models.
14 citations
,
September 2023 in “Frontiers in Nutrition” This source observed that while supplementation with pro-, pre-, and synbiotics showed some beneficial effects for PCOS-related outcomes, the evidence quality was deemed low to very low, highlighting the need for further well-designed randomized controlled trials in women with PCOS.
14 citations
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May 2016 in “Therapeutic advances in urology” This review examines the use of tadalafil and finasteride as a combined therapy for BPH, suggesting it may effectively reduce treatment-related sexual adverse events and improve symptom relief.
13 citations
,
August 2024 in “iScience” This study found that 3D spheroid culture reprogrammed mesenchymal stem cells into a uniform immunosuppressive phenotype, suggesting potential therapeutic applications for inflammatory diseases like psoriasis.
12 citations
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October 2018 in “Aging male/The aging male” This study found that prostate cancer aggressiveness in men with obesity is associated with changes in age, BMI, testosterone, and estradiol levels, and that adipocyte-secreted molecules increase cancer cell aggressiveness in vitro.