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The skin's internal clock affects healing, cancer risk, aging, immunity, and hair growth, and disruptions can harm skin health.

The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.

Asia has made significant progress in tissue engineering and regenerative medicine, but wider clinical use requires more development.

Tiny particles from stem cells help activate hair growth cells and encourage hair growth in mice without being toxic.

Minoxidil is the only FDA-approved topical drug for treating male or female pattern hair loss, and other medications like finasteride and dutasteride can also increase hair growth.

Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.

Researchers identified genes linked to coat color, body size, cashmere production, and high altitude adaptation in goats.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Using human fat tissue derived stem cells in micrografts can safely and effectively increase hair density in people with hair loss.

BMP2 and BMP7 have opposite roles in feather formation.

Minoxidil and finasteride effectively treat hair loss.

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

Mutant mice help researchers understand hair growth and related genetic factors.

Dermal Papilla cells are a promising tool for evaluating hair growth treatments.

The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.

Certain immune system proteins are important for skin healing but can cause problems if there are too many of them.

The p53 protein has complex, sometimes contradictory functions, including tumor suppression and promoting cell survival.

The extracellular matrix is crucial for controlling skin stem cell behavior and health.

The document concludes that the skin's immune system is complex, involving interactions with hair follicles, nerves, and microbes, and can protect or cause disease, offering targets for new treatments.

The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Lymphatic vessels are essential for hair follicle growth and skin regeneration.

Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.

The document concludes that both internal stem cell factors and external influences like the environment and hormones affect hair loss and aging, with potential treatments focusing on these areas.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

Cell-based therapies using dermal papilla cells and adipocyte lineage cells show potential for hair regeneration.

The evidence for using Low-Level Laser Therapy for hair loss is limited and more thorough research is needed.

Single Blimp1+ cells can create functional sebaceous gland organoids in the lab.