Search
for

    Glossary Wild-Type Mice

    laboratory mice with natural, unaltered genetic makeup

    Wild-Type Mice, often abbreviated as WT mice, are laboratory mice that have not been genetically modified and possess the natural, unaltered genetic makeup of their species. They serve as a standard or control group in experiments to compare against genetically altered mice, helping researchers understand the effects of specific genetic changes.

    Related Terms

    Sort by

    Research 30 of 1000+

    1. Impact of mTORC1 inhibition on keratinocyte proliferation during skin tumor promotion in wild‐type and BK5.Akt<sup>WT</sup> mice Molecular carcinogenesis · 2013 · 8 citations
    2. Interleukin-6 Null Mice Paradoxically Display Increased STAT3 Activity and Wound-Induced Hair Neogenesis Journal of Investigative Dermatology · 2016 · 16 citations
    3. Increased Rate of Hair Regrowth in Mice with Constitutive Overexpression of Del1 Journal of Surgical Research · 2007 · 6 citations
    4. Chymase Activities and Survival in Endotoxin-Induced Human Chymase Transgenic Mice International Journal of Medical Sciences · 2014 · 3 citations
    5. 768 Dermal fibroblast expression of lef1 is critical to normal skin and hair development and regenerative wound healing in mice Journal of Investigative Dermatology · 2022
    6. Safety of Whole-Body Abrogation of the TRF1 Shelterin Protein in Wild-Type and Cancer-Prone Mouse Models iScience · 2019 · 5 citations
    7. Local circadian clock gates cell cycle progression of transient amplifying cells during regenerative hair cycling Proceedings of the National Academy of Sciences of the United States of America · 2013 · 116 citations
    8. Docosahexaenoic acid slows inflammation resolution and impairs the quality of healed skin tissue Clinical Science · 2019 · 8 citations
    9. A Simple In Vivo System for Studying Epithelialization, Hair Follicle Formation, and Invasion Using Primary Epidermal Cells from Wild-Type and Transgenic Ornithine Decarboxylase-Overexpressing Mouse Skin Journal of Investigative Dermatology · 2001 · 13 citations
    10. Development and progression of alopecia in the vitamin D receptor null mouse Journal of cellular physiology · 2006 · 81 citations
    11. Order from disorder: Self-organization in mammalian hair patterning Proceedings of the National Academy of Sciences · 2006 · 91 citations
    12. Analysis of skin graft survival using green fluorescent protein transgenic mice Journal of medical investigation · 2007 · 19 citations
    13. A null mutation in the cystatin M/E gene of ichq mice causes juvenile lethality and defects in epidermal cornification 2002 · 66 citations
    14. Sebaceous gland abnormalities in fatty acyl CoA reductase 2 (Far2) null mice result in primary cicatricial alopecia PloS one · 2018 · 14 citations
    15. Fgf21 Deficiency Delays Hair Follicle Cycling and Modulates miRNA–Target Gene Interactions in Mice Biology · 2025
    16. Exogenous IGF-1 promotes hair growth by stimulating cell proliferation and down regulating TGF-β1 in C57BL/6 mice in vivo Growth Hormone & IGF Research · 2014 · 53 citations
    17. 026
Altered Skin Wound Healing in Homeobox Gene Msx-2 Knockout Mice Wound Repair and Regeneration · 2008
    18. 744 Role of Sdf1-Cxcr4 signaling in mouse appendage regeneration Journal of Investigative Dermatology · 2016
    19. Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis Journal of Dermatological Science · 2017 · 8 citations
    20. CD34 Expression by Hair Follicle Stem Cells Is Required for Skin Tumor Development in Mice Cancer Research · 2007 · 141 citations
    21. Expression of E6 and E7 papillomavirus oncogenes in the outer root sheath of hair follicles extends the growth phase and bypasses resting at telogen. PubMed · 2000 · 10 citations
    22. Promotion of mouse ameloblast proliferation by Lgr5 mediated integrin signaling Journal of Cellular Biochemistry · 2013 · 7 citations
    23. Generation of an intestinal‐specific hephaestin knockout mouse The FASEB Journal · 2010
    24. Anticonvulsant Activity of Progesterone and Neurosteroids in Progesterone Receptor Knockout Mice Journal of Pharmacology and Experimental Therapeutics · 2004 · 180 citations
    25. Mast cell deficient and neurokinin-1 receptor knockout mice are protected from stress-induced hair growth inhibition Journal of Molecular Medicine · 2005 · 76 citations
    26. Evaluation of Keratinocyte Proliferation and Differentiation in Vitamin D Receptor Knockout Mice Endocrinology · 2000 · 29 citations
    27. The alopecia areata phenotype is induced by the water avoidance stress test in <i>cchcr1</i>-deficient mice bioRxiv (Cold Spring Harbor Laboratory) · 2020
    28. The up‐regulation of 14‐3‐3 proteins in Smad4 deficient epidermis and hair follicles at catagen PROTEOMICS · 2008 · 14 citations
    29. Protein and amino acid composition of hair from mice carrying the naked (<i>N</i>) gene Genetics Research · 1984 · 12 citations
    30. Growth retardation and hair loss in transgenic mice overexpressing human H-ferritin gene Transgenic Research · 2012 · 8 citations