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Genetic changes in mice help understand skin and hair disorders, aiding treatment development for acne and hair loss.

This review discusses the essential roles and complex regulation of PP2A in various physiological processes and reports no clinical results; the authors highlight the need for further mouse model research to explore PP2A's therapeutic potential.

In this study, researchers found that the absence of P-selectin delays inflammatory cell recruitment and reepithelialization in fetal wounds, although scar formation still occurs in later gestation wounds.

This review discusses the limitations of animal models, particularly mice, in accurately predicting human skin wound healing outcomes and emphasizes understanding species-specific differences in skin characteristics for better translation to clinical settings.

This study found that the vitamin D receptor is crucial for initiating the postnatal hair follicular cycle in mice, preventing alopecia associated with its inactivation.