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Too much β-catenin activity can mess up the development of mammary glands and make them more like hair follicles.

Lysophosphatidic acid is important for skin health and disease, and could be a target for new skin disorder treatments.

Melatonin helps hair grow by activating a specific signaling pathway.

Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.

SOX9 helps determine stem cell roles by interacting with DNA and proteins that control gene activity.

The document concludes that hair follicles have a complex environment and our understanding of it is growing, but there are limitations when applying animal study findings to humans.

A genetic change in the EDAR gene causes the unique hair traits found in East Asians.

Mice with too much Claudin-6 have skin barrier problems and abnormal hair growth.

Rare changes in the KRT82 gene are linked to a higher risk of Alopecia Areata.

Wnt signaling is crucial for skin development and hair growth.

Keratin-associated proteins have ancient origins and were used for different purposes before being adapted for hair in mammals.

The Wnt signaling pathway is not a major factor in the development of keratoacanthoma, a type of skin tumor.

Certain long non-coding RNAs are important for controlling hair growth cycles in sheep.

The conclusion is that proper signaling is crucial for hair growth and development, and errors can lead to cancer or hair loss.

Men with sleep apnea and low iron levels are more likely to have male-pattern baldness, especially if they have a family history of hair loss.

Adult esophageal cells can start to become like skin cells, with a key pathway influencing this change.

The study provides insights into hair growth mechanisms in yaks.

A compound named ZCZ90 can increase muscle spindle firing, potentially helping treat muscle spasms and hypertension.

SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.

Pitx2 helps outer root sheath cells differentiate but can't start hair growth on its own.

French maritime pine bark extract significantly increased hair density in menopausal women.

Animal models, especially mice, are essential for advancing hair loss research and treatment.

The genes KRT25 and SP6 affect curly hair in horses, with KRT25 also causing hair loss. If both genes are mutated, the horse gets curly hair and hair loss. KRT25 can hide the effect of SP6.

Researchers created a mouse with the same mutation as humans with trichothiodystrophy, showing similar symptoms and confirming the condition is due to defects in DNA repair and gene activity.

Signaling pathways are crucial for hair growth in goats.

Valproic acid helps delay hair loss and increases survival time for high-grade glioma patients undergoing radiation therapy.

PPARγ is essential for maintaining healthy skin, controlling inflammation, and ensuring proper skin barrier function.

The KNU implanter for hair transplants showed a high survival rate of 90%+ for transplanted hairs after 6 months, with benefits like natural hair direction and fewer scars.

Rapamycin treatment helps with mitochondrial disease by reducing PKC levels.

Boys with less severe EDA mutations in XLHED have milder symptoms and better sweat and hair production.