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      A Matter of Life and Death: Self-Renewal in Stem Cells

      research A matter of life and death: self‐renewal in stem cells

      150 citations , December 2012 in “EMBO Reports”
      This review explores the mechanisms of adult stem cell self-renewal, using skin as a model, and reports no new results but raises important unanswered questions in the field.
      Alopecia Areata: A Multifactorial Autoimmune Condition

      research Alopecia areata: A multifactorial autoimmune condition

      148 citations , December 2018 in “Journal of autoimmunity”
      This review discusses genetic and environmental factors contributing to autoimmunity in alopecia areata and reports no new clinical findings, emphasizing the need for further study on its aetiology and pathophysiology.
      Hormone Therapy for Transgender Patients

      research Hormone therapy for transgender patients

      146 citations , December 2016 in “Translational Andrology and Urology”
      This review discusses the creation of transgender-specific guidelines by WPATH and the Endocrine Society, based mostly on clinical experience, and reports no new results.
      Epidemiology and Burden of Alopecia Areata: A Systematic Review

      research Epidemiology and burden of alopecia areata: a systematic review

      144 citations , July 2015 in “Clinical, Cosmetic and Investigational Dermatology”
      This review reports that alopecia areata affects about 2% of people globally and is linked with psychiatric and medical comorbidities, highlighting its significant disease burden.
      K ATP Channels and Cardiovascular Disease

      research K ATP Channels and Cardiovascular Disease

      144 citations , March 2013 in “Circulation Research”
      This study reports that mutations in the SUR2 gene are linked to Cantu syndrome, highlighting the role of KATP channels in cardiovascular health and potential new therapies.
      Tactile Innervation Densities Across the Whole Body

      research Tactile innervation densities across the whole body

      142 citations , September 2020 in “Journal of neurophysiology”
      This study estimates that young adults have about 230,000 tactile afferent fibers innervating their skin, with density varying by region and decreasing with age.
      A Perspective on RNAi-Based Biopesticides

      research A Perspective on RNAi-Based Biopesticides

      140 citations , February 2020 in “Frontiers in Plant Science”
      This article discusses the potential of RNA-based biopesticides for sustainable agriculture and reports no new experimental results; it highlights the need for improved delivery systems and regulatory development to enhance deployment.
      Androgenetic Alopecia in Women

      research Androgenetic Alopecia in Women

      139 citations , June 2003 in “Journal of Investigative Dermatology Symposium Proceedings”
      This article reviews androgenetic alopecia in women, highlighting diagnosis criteria and noting that topical minoxidil is currently the only proven treatment for hair growth; it reports no clinical trial findings.
      Stem Cell Dynamics in the Hair Follicle Niche

      research Stem cell dynamics in the hair follicle niche

      135 citations , December 2013 in “Seminars in Cell & Developmental Biology”
      This review examines the literature on the molecular and cellular makeup of the hair follicle niche and how it influences stem cell behavior during hair regeneration, but does not provide new experimental results.
      The Influence of Androgens on Insulin Resistance

      research The influence of androgens on insulin resistance

      135 citations , March 1984 in “Fertility and sterility”
      In this study, insulin resistance in polycystic ovary syndrome was highly correlated with unbound testosterone and sex hormone-binding globulin, rather than luteinizing hormone or peripheral androgen metabolism.
      Acne, the Skin Microbiome, and Antibiotic Treatment

      research Acne, the Skin Microbiome, and Antibiotic Treatment

      134 citations , January 2019 in “American journal of clinical dermatology”
      This review summarizes recent research on the skin microbiome's role in acne development and how antibiotic treatments affect skin microbes, but it reports no new clinical results.
      Androgenetic Alopecia and Microinflammation

      research Androgenetic alopecia and microinflammation

      131 citations , August 2000 in “International Journal of Dermatology”
      Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
      Hormesis And Medicine: Biphasic Dose-Response Relationship

      research Hormesis and medicine

      127 citations , June 2008 in “British Journal of Clinical Pharmacology”
      This study supports the conclusion that the hormetic dose-response model is the most prevalent and fundamental model in biological and biomedical sciences, applicable to a wide range of clinical conditions.
      Structural Abnormalities of the Hair Shaft

      research Structural abnormalities of the hair shaft

      126 citations , January 1987 in “Journal of The American Academy of Dermatology”
      This article reviews the classification of hair shaft abnormalities, outlining their diagnostic features, but does not present new research findings.
      Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      research Targeting the Janus Kinase Family in Autoimmune Skin Diseases

      124 citations , October 2019 in “Frontiers in Immunology”
      This review discusses the role of the JAK-STAT pathway in autoimmune skin diseases and suggests potential therapeutic benefits of JAK inhibitors, but reports no new experimental results.