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Testosterone treatment effectively causes male physical development in transgender male adolescents but may lead to side effects like acne, higher BMI and blood pressure, lower good cholesterol, and decreased bone density.

Hair color production in mice is closely linked to the hair growth phase and may also influence hair growth itself.

Elastic Net DNA methylation clocks are inaccurate for predicting age and health status; a "noise barometer" may better indicate aging and disease.

Pilonidal sinus disease is linked to more severe hidradenitis suppurativa.

New drug delivery methods can make natural compounds more effective and stable.

Hormonal imbalances, often indicating conditions like PCOS, are common in women with hard-to-treat acne, and a treatment approach addressing these imbalances may be needed.

Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.

Eating a balanced diet with vitamins, micronutrients, and antioxidants is important for hair health and can help with hair loss.

Treating sleep apnea in young obese women with PCOS can improve heart health and insulin sensitivity.

The Middle East and Africa need better data, treatment consensus, and support for Alopecia Areata.

People with alopecia areata have similar overall death rates as others but higher risks of death from self-harm, psychiatric issues, and lung cancer in certain cases.

Tofacitinib was effective in treating hair loss in two patients with alopecia universalis.

TGF-β2 plays a key role in human hair growth and development.

Skin cells can help create early hair-like structures in lab cultures.

Early-onset AGA shows different hair and metabolic characteristics compared to normal-onset AGA.

Alopecia areata patients, especially women with nail issues or atopic diseases, are at higher risk for other autoimmune diseases.

Loss of OGG1 increases skin inflammation and auto-antibodies in lupus.

Finasteride may help treat chronic CSC, improving vision.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Light scatters differently from elliptical hair fibers than from circular ones, and a new model better predicts this behavior, especially for shiny highlights.

Hydrogels combined with extracellular vesicles and 3D bioprinting improve wound healing.

Early diagnosis of GLPLS is crucial to prevent complications, but scarring alopecia is irreversible.

The current system can't fully test all combination treatments, so alternative methods and regulatory flexibility are needed.

Dihydrotestosterone increases the activity of an enzyme in pubic skin cells that converts testosterone to dihydrotestosterone.

The document concludes that recognizing specific histological features of different nonscarring alopecias is crucial for accurate diagnosis and understanding hair loss progression.

PCOS is a long-term condition that needs more research for better understanding and treatment.

Stem cells could improve hair growth and new treatments for baldness are being researched.

COVID-19 changed dermatology by increasing telemedicine and highlighting healthcare disparities.

Low selenium intake may delay puberty in boys but not in girls.

Platelet-rich plasma is an effective and safe treatment for male pattern hair loss.