26 citations
,
May 1984 in “Journal of Parenteral and Enteral Nutrition” In this study, a 54-year-old woman with short bowel syndrome developed biotin deficiency and associated symptoms while on home parenteral nutrition lacking biotin, which improved significantly after supplementation.
25 citations
,
June 2014 in “Journal of Endocrinology/Journal of endocrinology” This study found that local androgen biosynthesis and metabolism in human sebaceous glands play a crucial role in sebum synthesis and secretion.
21 citations
,
November 2011 in “Veterinary Pathology” This study evaluated skin and hair color variations in different mouse strains, highlighting the association between hair cycle stages and skin pigmentation to better understand these features and their implications.
20 citations
,
December 2003 in “Journal of Cosmetic and Laser Therapy” This study found that an 800-nm diode laser was effective for reducing pigmented hair and extending hair plucking intervals, with most patients tolerating the procedure well without anesthetics.
19 citations
,
May 2007 in “Dermatologic therapy” The document concludes that various treatments, including laser therapy, are effective for managing pseudofolliculitis barbae, especially in darker skin types.
19 citations
,
January 2001 in “Journal of cutaneous laser therapy” This study found that the long-pulse Nd:YAG laser effectively reduces unwanted facial hair across various skin types, with hair regrowth delayed significantly longer than with self-applied methods.
18 citations
,
June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” In this mouse study, hair growth defects associated with the Gk5 null allele were partially alleviated by simvastatin treatment, suggesting GK5 plays a key role in skin-specific cholesterol regulation.
18 citations
,
August 2014 in “Lipids” This study found that unsaturated fatty acids are more abundant in the cortex of human hair than on its surface, and steryl glycoside-like lipids may help bind the cuticle to the cortex.
17 citations
,
June 2011 in “Dermatologic Surgery” This abstract provides no results; it contains subscription and journal information and does not discuss any study or findings.
16 citations
,
July 2012 in “Current pharmaceutical biotechnology” This review discusses the pathogenesis of common sebaceous gland diseases and their molecular pathways, but it reports no new clinical findings.
15 citations
,
May 2018 in “Open Access Macedonian Journal of Medical Sciences” This double-blind control study found that an ointment containing propolis (50%) and aloe vera (3%) led to significant improvement in 64.4% of patients with mild to moderate psoriasis over 12 weeks, compared to no significant improvement in the placebo group.
15 citations
,
August 1998 in “Australasian journal of dermatology” This review discusses various treatments for hirsutism, including cosmetic techniques, anti-androgens like spironolactone, and new drugs such as finasteride and flutamide, but it reports no new clinical results.
14 citations
,
January 2006 in “Australasian journal of dermatology” This case report describes an atypical presentation of alopecia areata in a 53-year-old postmenopausal woman, which may resemble frontal fibrosing alopecia and complicate diagnosis.
12 citations
,
February 2006 in “Lipids” This study found that in Japanese, German, and American females, changes in hair lipid patterns with age may reflect alterations in sebum excretion and affect hair texture.
11 citations
,
March 2009 in “Bioorganic & Medicinal Chemistry Letters” This study reports that 4-(alkylthio)- and 4-(arylthio)-benzonitriles showed moderate sebum reduction as androgen receptor antagonists when applied topically in a validated animal model.
11 citations
,
February 2008 in “British journal of nursing” This article reviews idiopathic hirsutism, focusing on its definition, diagnosis, causes, and treatment options, without presenting new clinical findings.
10 citations
,
November 2015 in “Elsevier eBooks” This review outlines the development and functional requirements of modern wound dressing materials and describes preparation methods and product performance, but reports no new clinical findings.
10 citations
,
August 2014 in “Skin research and technology” This study found that variations in sleep patterns, free testosterone, and 5-alpha-reductase type 1 activity are associated with changes in sebum excretion in women, which may contribute to variability in acne studies.
10 citations
,
January 2013 in “Journal of The European Academy of Dermatology and Venereology” In this study, a square pulse, low-fluence IPL device used at home significantly reduced terminal hair count by 87% six months post-treatment, with evidence of hair miniaturization similar to professional laser treatments.
10 citations
,
January 2005 in “Dermatology” This review discusses possible links between certain skin conditions and elevated coronary disease risk, but reports no new results and highlights methodological flaws in existing studies.
9 citations
,
May 2021 in “Archives of Dermatological Research” This study concluded that while home-based intense pulsed light, laser diodes, radiofrequency, and light-emitting diode devices are recommended for certain skin conditions, ultraviolet B phototherapy for psoriasis showed mixed evidence compared to clinic treatments.
9 citations
,
May 2005 in “Facial plastic surgery” This article reviews safe and effective hair removal options for dark-skinned patients and reports no new clinical results.
9 citations
,
January 2015 in “Springer eBooks” This article reviews the diagnostic criteria and management strategies for polycystic ovary syndrome but reports no new clinical findings; it highlights associated health risks and recommended treatments.
9 citations
,
July 2014 in “Experimental Dermatology” This study suggests that while PTH rP initially seemed to shorten the hair cycle by transitioning hair follicles from anagen to catagen, more relevant models indicate it ultimately accelerates and stimulates hair growth.
9 citations
,
March 2005 in “Aesthetic surgery journal” This study reported that long-pulse alexandrite laser treatment achieved an overall hair reduction rate of 80.8% among patients, with minimal cases of hypo- or hyperpigmentation.
8 citations
,
January 2019 in “Annals of Dermatology” Among cultured sebocytes, this study found that bilobetin significantly inhibited lipid production induced by IGF-1, suggesting potential for use in acne treatment.
8 citations
,
September 2017 in “The Journal for Nurse Practitioners” This study observed that most women with PCOS in the United States use adaptive coping strategies, while those with higher psychological severity may resort to maladaptive coping methods.
7 citations
,
April 2018 in “Molecular Medicine Reports” This study found that BeauTop, a supplement containing several traditional Chinese herbs, may promote hair growth in mice with alopecia, potentially by modulating EGF and FGF-7 levels.
7 citations
,
July 2014 in “BMJ case reports” This article reviews the rare skin disorder ichthyosis with confetti, highlighting the potential for future therapies using revertant stem cells, and reports no new clinical results.
6 citations
,
August 2014 in “Toxicologic pathology” This study found that prolonged inhibition of DGAT1 in mice and dogs led to atrophy of sebaceous glands, with mice also experiencing alopecia, suggesting potential skin-related risks for humans using DGAT1 inhibitors.