June 2021 in “SWU eJournals System (Srinakharinwirot University)” The study found that cyproterone acetate could be released over 15 days using coconut oil mixed with certain wax inhibitors, though further safety studies are needed.
This study reported that a topical hair tonic containing a 7.5% talok leaf and 2% pare leaf extract combination promoted hair growth in female Wistar rats similarly to minoxidil, showing a 64.71% increase in hair growth with no significant difference from minoxidil in statistical analysis.
May 2023 in “Frontiers in Pharmacology” Water extract of cacumen platycladi helps hair growth by affecting specific cell pathways.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” In this research, lipidomic, proteomic, and metabolomic analyses of exosomes from seven Ashwagandha seed batches revealed that Ashwagandha-derived exosome-like nanovesicles can up-regulate VEGF-A production and promote hair growth in human models tested outside the body.
This narrative review examined the potential of hibiscus leaves and apple skin as natural ingredients for hair tonics and reported their effectiveness in addressing hair loss, highlighting properties like strong antioxidant content and ability to strengthen hair roots.
September 1973 in “Primates”
4 citations
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February 2021 in “Journal of Cosmetic Dermatology” This study found that pumpkin seed oil significantly improved hair parameters in females with pattern hair loss, demonstrating potential as a treatment comparable to minoxidil 5% foam.
16 citations
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April 2022 in “Journal of Food Quality” This study found that blueberry waste in Australia has high phenolic content and antioxidant potential, suggesting potential uses in food, pharmaceutical, and nutraceutical industries.
November 2023 in “International Journal of Cosmetic Science” This study found that a wheat polar lipid complex supplement significantly reduced hair loss and improved hair growth and volume in women experiencing acute hair shedding, including postmenopausal women.
1 citations
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October 2015 in “Interest : Jurnal Ilmu Kesehatan” In this study, both gel and microemulsion formulas containing waru leaves and Java Tamarind extracts were found to have similar in vivo hair growth activity in rabbits.
5 citations
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September 2020 in “DOAJ (DOAJ: Directory of Open Access Journals)” This study found that a hair serum containing amla extract, freeze-dried coconut water, selenium, sandalwood odorant, and peanut shell extract significantly improved hair growth, density, and reduced hair fall after 90 days in healthy volunteers.
May 2026 in “Waste and Biomass Valorization”
3 citations
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September 2018 in “MOJ Toxicology” This review discusses the medicinal properties of Alpinia zerumbet Roxb. and highlights its potential for further research, but provides no new clinical results.
March 2006 in “Hair transplant forum international” This article discusses the challenges hair restoration physicians face in obtaining the perfect donor strip for hair transplants, with no new findings reported.
May 2026 in “Zenodo (CERN European Organization for Nuclear Research)” This review concludes that herbal formulations containing Ziziphus mauritiana and Black Seed Oil may offer a promising natural alternative for managing hair-related issues like dandruff, hair fall, and scalp irritation.
October 2025 in “Dermatology and Therapy” This study observed that adults with thinning hair who ingested a patented botanical-based supplement experienced significant increases in hair shaft diameter and reductions in hair breakage over 180 days, suggesting improved hair strength and length across various demographic groups.
March 2026 in “Mendeley Data” This tool was developed to enhance reproducibility and sensitivity in measuring partial hair regrowth in alopecia areata patients, particularly those undergoing JAK inhibitor therapy, using scalp photographs.
January 2024 in “EduChemia (Jurnal Kimia dan Pendidikan)” This study found that an oleogel combining watermelon rind extract and orange peel essential oil led to 100% hair growth in male DDY mice, highlighting these extracts as potential nutrients for treating hair loss.
1 citations
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January 2018 in “Journal of microscopy and ultrastructure” In this study, researchers used SEM/SDD-EDS to identify waterborne minerals like calcium and aluminum in the scalp hair cuticle of individuals using treated or untreated water for hair washing, finding that prior application of coconut oil or conditioners can prevent calcium uptake.
July 2021 in “Research Square (Research Square)” In this study, the ethyl acetate extract of Semecarpus anacardium Linn leaves was reported to induce cytotoxicity in cancer cells, cause cell cycle arrest, and suppress tumor growth in mice.
April 2024 in “Current journal of applied science and technology” This study developed an ointment from palm kernel oil and shea butter, which demonstrated improved hair growth in rabbits and may inform the creation of non-harmful hair growth products for humans.
6 citations
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January 2018 in “Dermato-endocrinology” This study found that acanthosis nigricans in the knuckles correlates with higher insulin and HOMA-IR values, potentially serving as an early, accessible marker for insulin resistance even without excess weight.
February 2010 in “Journal of the American Academy of Dermatology” The shampoo and conditioner improved dry, damaged hair significantly after three uses.
In this study, 20% whale oil applied to mice was observed to promote hair growth more effectively than a control or 3% minoxidil, showing increased hair follicles and thicker subcutaneous tissue.
April 2025 in “Mutiara Jurnal Penelitian dan Karya Ilmiah” In this study of Beauty and Aesthetics students, researchers found that using a hair tonic made from Green Spinach Leaves significantly reduced hair loss when applied weekly, compared to a control, but no significant difference was observed when increasing application to twice weekly.
1 citations
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February 2022 in “International Journal of Health and Pharmaceutical (IJHP)” This study found that a combination of cantigi and henna leaf extracts, in a 1:2 ratio, demonstrated the strongest antioxidant activity with an IC50 value of 29.85 µg/mL.
December 2023 in “Advances in Integrative Medicine” This case study suggests that using Boswellia sacra (Frankincense) both orally and topically, along with diet and lifestyle changes, may rapidly resolve pilonidal sinus disease, a condition commonly marked by high recurrence, although no prior studies have investigated this treatment for PNS.
13 citations
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February 2019 in “Journal of Microencapsulation” This study focused on designing a niosome formulation that encapsulates pumpkin seed oil for topical use, achieving high entrapment efficiency and stability over three months.
March 2026 in “International Journal of Pharmaceutics and Drug Analysis” This study formulated an herbal anti-dandruff shampoo using jackfruit seed extract and evaluated its effectiveness against Malassezia furfur, finding that the fourth formulation exhibited both strong antifungal activity and stability, suggesting a natural alternative to synthetic hair care products.
2 citations
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January 2021 in “Journal of Cosmetics, Dermatological Sciences and Applications” In this study, phenol-enriched olive mill wastewater extract positively influenced hair growth in vitro by promoting human dermal papilla cell proliferation, increasing insulin-like growth factor-1 secretion, and reducing reactive oxygen species, suggesting it may be beneficial for hair care.