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The Endocrine Society advised against routine testosterone therapy for women, citing a need for more research on long-term safety and a clear definition of androgen deficiency.

PCOS is a complex disorder in women that can lead to various health risks and requires personalized treatment.

Exposure to too much androgen before birth might cause polycystic ovary syndrome later in life.

The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.

Creating stronger blockers for skin enzymes might lead to better treatment for conditions like acne and excessive hair growth.

Acne affects most teenagers and can continue into adulthood, with various treatments available that show improvement but have concerns like antibiotic resistance and side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Biomaterials with MSC-derived substances could improve tissue repair and have advantages over direct cell therapy.

Melatonin may help with sleep issues, depression, and cancer, but more research is needed.

Skin fat cells help with skin balance, hair growth, and healing wounds.

Minoxidil and finasteride treat hair loss in men, while minoxidil treats hair loss in women.

Lifestyle changes can improve body composition, excess male hormone levels, and insulin resistance in women with PCOS.

Male and female bodies respond differently to stress, influenced by hormones and development stages, with implications for stress-related diseases.

Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.

Women with PCOS are more likely to have impaired glucose tolerance and type 2 diabetes, especially if they are Asian or obese.

Erectile dysfunction is increasingly common in men under 40, with many physical and psychological causes, and various treatment options available.

Different types of skin cells have unique genetic markers that affect how likely they are to spread cancer.

A substance called DKK-1 increases in balding areas and causes hair cells to die when exposed to DHT.

The document concludes that the exact way alcohol causes harm to fetal development is unknown, but it significantly affects nutrient transport to the fetus and a safe level of alcohol during pregnancy is not determined.

Hormone treatments for transgender individuals generally improve mental health and physical transition, with some health risks that require medical supervision.

Scientists made working salivary glands in mice using bioengineered cells, which could help treat dry mouth.

People who are more materialistic often expect life changes from buying things, leading to more debt and credit misuse.

Testosterone therapy in transgender men has both desired effects like increased muscle mass and potential health risks such as higher cardiovascular risk.

Some skin medications are safe during pregnancy and breastfeeding, but others can harm the baby and should be avoided.

DrugNet effectively identifies new uses for existing drugs and may save resources in drug development.

The document concludes that recognizing and treating cutaneous lupus erythematosus early is crucial for managing the skin and potential systemic symptoms.

Methotrexate treats various disorders by inhibiting DNA synthesis, but careful monitoring is needed to avoid toxicity and manage side effects.

Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.

Trilostane effectively improved symptoms in dogs with a certain adrenal gland disorder.