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research PLATELET RİCH PLASMA RESULTS IN THE TREATMENT OF FEMUR HEAD AVASCULAR NECROSIS
This study found that using a new method to apply platelet-rich plasma during surgery improved early outcomes for patients with hip avascular necrosis, including those with a history of Covid-19.
research Serum Vitamin B12 in chronic telogen effluvium patients: A case–control study
This study found that Vitamin B12 deficiency was more common in patients with chronic telogen effluvium than in healthy controls.
research CCDC22 and CCDC93, two potential retriever-interacting proteins, are required for root and root hair growth in Arabidopsis
This study identifies two new proteins, CCDC22 and CCDC93, essential for root and root hair growth in Arabidopsis, and demonstrates their genetic link to a VTI13-dependent vacuolar trafficking pathway.
research Clinical Snippets
A bull with a gene mutation was asymptomatic, synthetic retinoids cause hair loss, and new therapeutic targets were identified for skin diseases.
research Activation of TRPV3 Regulates Inflammatory Actions of Human Epidermal Keratinocytes
This study found that TRPV3 ion channels on human epidermal keratinocytes suppress cell proliferation, induce cell death, and trigger a proinflammatory response, suggesting a role in cutaneous inflammatory processes.
research Treatme nt of vitamin-D and calcium to children with hair defluvium
This study found that treating children with hair defluvium using vitamin-D and calcium significantly improved symptoms, with a total effective rate of 93.3%.
research The Chinese State Food and Drug Administration has issued Sinovac Biotech a New Drug Certificate approving its split influenza vaccine
China approved Sinovac's flu vaccine, Japan approved RiUP for female hair loss, and Nippon Kayaku's three cancer drugs.
research Recurrent bacterial vaginosis and Netherton's syndrome
This report details a case of severe recurrent bacterial vaginosis in a woman with Netherton's syndrome.
research Folliculin, the Product of the Birt-Hogg-Dube Tumor Suppressor Gene, Interacts with the Adherens Junction Protein p0071 to Regulate Cell-Cell Adhesion
This study found that dysregulation of the folliculin-p0071 interaction may lead to changes in cell adhesion and signaling, contributing to conditions like emphysema and renal cell carcinoma.
research The Effect of Butin on the Vitiligo Mouse Model Induced by Hydroquinone
This study in mice found that butin, a component of Vernonia anthelmintica, increased melanin production and related proteins while reducing oxidative stress markers in a model of hydroquinone-induced vitiligo, suggesting support for its traditional use against this condition.
research Breaking the Hair-Loss Barrier: Pattern-Wise Efficacy of Verilich Serum
This prospective observational study evaluated the use of Verilich serum for hair loss and found that 71.4% of chronic telogen effluvium patients saw significant improvement in hair shedding within 2 months, with no adverse events reported.
research Epithelial cell migration on laminins
This study suggests that CD151-integrin complexes inhibit epithelial cell migration, and that disruption of these complexes enhances migration, regulated by Rho GTPase activation differences on distinct laminins.
research Hair Growth Promotion Effect of Nelumbinis Semen Extract with High Antioxidant Activity
This study found that Nelumbinis Semen extract may promote hair growth and reduce hair loss by increasing VEGF and IGF-1 expression and decreasing TGF-β1 in human dermal papilla cells and mice.
research Vascular endothelial cells as signaling niches for epithelial stem cells in the skin
This review discusses the potential role of vascular endothelial cells as signaling niches influencing epithelial stem cell states in the skin, emphasizing the need for further exploration in this area.
research Update in Hematology and Oncology: Evidence Published in 2010
This review discusses notable hematology and oncology studies from 2010, including treatments for venous thromboembolism, sickle cell disease, and superficial venous thrombosis, without presenting new clinical results.
research Ligand‐Independent Actions of the Vitamin D Receptor: More Questions Than Answers
This review discusses the role of the unliganded vitamin D receptor in hair follicle cycling and tumor formation in mice and reports no new experimental findings.
research Tectoridin Stimulates the Activity of Human Dermal Papilla Cells and Promotes Hair Shaft Elongation in Mouse Vibrissae Hair Follicle Culture
This study found that tectoridin, an isoflavone from Rhizoma Belamcandae, may stimulate hair growth by activating Wnt signaling in human and mouse cell cultures.
research Titagen® for total wellness: results from a randomised, placebo controlled clinical study on adults for osteoarthritis, improvement in skin, nail and health
In this randomized, placebo-controlled study, Titagen® was found to improve skin, hair, and nail health in adults consuming 5g daily, and reduce pain and improve quality of life for osteoarthritis patients taking 10g daily, without related adverse events.
research Oral tofacitinib: a promising treatment in atopic dermatitis, alopecia areata and vitiligo
This article discusses the potential of oral tofacitinib as a treatment for atopic dermatitis, alopecia areata, and vitiligo, without presenting new clinical results.
research Anti‐keratin Monoclonal Antibody against Basal Cell Epithelioma Keratin: BKN‐1
This study reports that the monoclonal antibody BKN-1 specifically stained basal cell epithelioma cells and certain normal skin structures, indicating a similarity in keratin expression between the tumor and follicular epithelium below the isthmus portion.
research Use of the drug Wolvit® (biotin 5 mg) in treatment of defuse telogenous alopecia
In this study, the researchers reported that women with diffuse telogen alopecia who took Wolvit® (biotin 5 mg) daily for 3 months showed a significant decrease in hair in the telogen phase and an increase in hair thickness and growth speed.
research Classification of Visually Similar Scalp Diseases using Deep Learning: A Hybrid CNN-VIT Approach with Cross-Attention Fusion
In this study, researchers developed a hybrid deep learning model called ScalpViT that accurately diagnosed scalp diseases with 94.3% accuracy, surpassing existing methods like ResNet-50 and EfficientNet-B3, and providing visual explainability for clinicians using GradCAM and Attention Rollout techniques.
research DrugNet: Network-based drug–disease prioritization by integrating heterogeneous data
This study found that DrugNet, a network-based prioritization method, effectively improves drug repositioning tasks, achieving high performance in validation tests and clinical trial comparisons.
research Targeted delivery of extracellular vesicles: the mechanisms, techniques and therapeutic applications
This review discusses the mechanisms and engineering techniques for enhancing the targeted delivery of extracellular vesicles in therapies but reports no new clinical findings; the authors encourage further exploration to advance clinical applications.
research Activation of AR Sensitizes Breast Carcinomas to NVP-BEZ235's Therapeutic Effect Mediated by PTEN and KLLN Upregulation
This study found that AR-positive breast cancer cell lines are more sensitive to the dual PI3K/mTOR inhibitor NVP-BEZ235 compared to AR-negative cells.
research Efficacy and safety evaluations of topical proretinal nanoparticles
This study found that proretinal nanoparticles, applied topically, are safe and effective for penetration into hair follicles, enhancing retinoid biological activity in the skin while reducing irritation compared to conventional retinal formulations.
research 783 Influence of TNF gene polymorphism in patients with acute and fulminnant hepatitis
research Regulation of Involucrin Gene Expression
This review discusses the regulation of involucrin gene expression, focusing on transcription factors and signaling pathways, and reports no new experimental findings.
research Decision‐Making Regarding the Administration of Live Vaccines to Patients With a FOXN1 Heterozygous Missense Variant
This report examines the cautious approach to administering live vaccines to an infant with a heterozygous FOXN1 variant, noting the importance of monitoring TREC levels and immune function indicators in guiding vaccination decisions in such cases.