Update in Hematology and Oncology: Evidence Published in 2010
April 2011
in “
Annals of Internal Medicine
”
TLDR Rivaroxaban and fondaparinux are effective for certain blood conditions, and hydroxyurea helps in sickle cell disease.
This update from 2011 reviewed significant hematology and oncology articles published in 2010, highlighting key findings relevant to internists. Notable studies included the use of rivaroxaban for venous thromboembolism treatment without initial parenteral anticoagulation, evidence against the necessity of parenteral anticoagulation for recurrent pregnancy loss, and real-world data supporting hydroxyurea's effectiveness in sickle cell disease. Additionally, it suggested considering fondaparinux for patients with extensive superficial venous thrombosis. These findings were considered particularly impactful for clinical practice at the time.