January 2023 in “International Journal of Contemporary Pediatrics” A rare genetic disease causes rickets and often hair loss in young children, which can improve with specific treatments.
139 citations,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
138 citations,
November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
107 citations,
March 2014 in “BoneKEy Reports” Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
46 citations,
March 2001 in “Journal of endocrinological investigation” 5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.
45 citations,
December 2006 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Vitamin D and its receptor are essential for hair growth, cell regulation, immune function, and heart health.
36 citations,
February 2007 in “Journal of biological chemistry/The Journal of biological chemistry” The vitamin D receptor can work without its usual activating molecule.
20 citations,
June 2020 in “Journal of Advanced Research” High-dose vitamin A and E with zinc improved blood sugar control and insulin function in diabetics, but may cause hair loss.
18 citations,
July 2010 in “Journal of steroid biochemistry and molecular biology/The Journal of steroid biochemistry and molecular biology” The vitamin D receptor helps regulate skin and hair health independently of its usual vitamin D ligand.
18 citations,
November 2009 in “Calcified tissue international” A genetic mutation caused severe rickets and alopecia in an Indian patient, but high-dose calcium and phosphate treatment improved their condition.
16 citations,
June 2017 in “DOAJ (DOAJ: Directory of Open Access Journals)” Low levels of vitamin B12 and ferritin are linked to early hair graying.
15 citations,
August 2021 in “Reviews in endocrine and metabolic disorders” COVID-19 and hypopituitarism (reduced pituitary gland function) are linked, with the latter's related health issues potentially worsening COVID-19 outcomes, and COVID-19 possibly increasing risk for pituitary complications.
15 citations,
March 2000 in “The journal of investigative dermatology/Journal of investigative dermatology” As skin cells mature, vitamin D receptor levels decrease while retinoid X receptor α levels increase.
13 citations,
August 2020 in “Journal of Laparoendoscopic & Advanced Surgical Techniques” Biotin supplements are generally ineffective in preventing hair loss after sleeve gastrectomy.
13 citations,
July 2020 in “World journal of stem cells” Vitamin D and calcium are important for skin stem cell function and wound healing.
12 citations,
September 2014 in “Bone” A vitamin D receptor mutation causes rickets and affects immune responses.
10 citations,
February 2017 in “Hormone Molecular Biology and Clinical Investigation” Metformin effectively improves metabolic symptoms in women with PCOS, while alfacalcidiol does not have a significant impact.
3 citations,
November 2021 in “World Journal of Clinical Pediatrics” Vitamin D might help treat some types of hair loss, but more research is needed.
3 citations,
January 2017 in “Journal of Pakistan Association of Dermatology” Women with certain types of hair loss may have low iron levels, and iron supplements could help.
1 citations,
March 2014 in “Senses and Sciences” A supplement with Serenoa repens improved hair loss in a patient.
Good nutrition may help prevent premature hair graying.
January 2024 in “Polski Merkuriusz Lekarski” Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.
October 2023 in “Journal of Preventive Diagnostic and Treatment Strategies in Medicine” Low ferritin and Vitamin D levels may cause hair loss after COVID-19.
September 2023 in “Frontiers in medicine” The mTOR signaling pathway is crucial for hair health and targeting it may lead to new hair loss treatments.
July 2022 in “International Journal of Contemporary Pediatrics” Two siblings with a rare type of rickets and hair loss had low vitamin D levels, which is not typical for their condition.
July 2018 in “British Journal of Dermatology” Hair regrowth was seen in 83% of children with alopecia, immune system plays a role in the condition, and various treatments showed effectiveness for hair and nail disorders.
November 2016 in “Zoo biology” Adding more vegetables and fruits improved capybaras' coat quality and health.
September 2016 in “Springer eBooks” Looking older on the outside might be linked to aging faster on the inside and can be affected by lifestyle choices and health risks.
467 citations,
October 2014 in “European Journal of Endocrinology” The European Society of Endocrinology advises individualized long-term management for PCOS, focusing on lifestyle changes, accurate diagnosis, and treatments for associated health risks and symptoms.
276 citations,
April 2003 in “Molecular endocrinology” Vitamin D is important for bones, hair, blood pressure, and breast development.