42 citations,
July 2007 in “Journal of Biological Chemistry” Most Hairless gene mutations reduce its ability to work with the Vitamin D Receptor, which might explain a certain type of hair loss.
32 citations,
December 2017 in “International Journal of Molecular Sciences” Low vitamin D might be linked to certain types of hair loss, and supplements could help, but more research is needed.
28 citations,
January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
26 citations,
March 2014 in “Journal of cutaneous medicine and surgery” Topical vitamin D is useful for some skin conditions but not effective for others, and more research is needed.
13 citations,
December 2012 in “Frontiers in bioscience” Vitamin D and estrogen may help protect heart and kidney health, and maintaining sufficient vitamin D levels could be especially beneficial for African Americans, postmenopausal women, and people with chronic kidney disease.
6 citations,
November 2017 in “Scientific reports” The R343H mutation in the VDR gene causes vitamin D-resistant rickets with alopecia by impairing specific gene activity.
5 citations,
January 1970 in “Journal of Nepal Paediatric Society” Hair loss can be a key sign of a rare type of rickets when vitamin D treatment doesn't work and advanced tests aren't available.
2 citations,
January 2019 in “International journal of medicine in developing countries” Many people in Majmaah city, Saudi Arabia, don't know much about vitamin D deficiency and don't practice good vitamin D habits, with few linking it to hair loss.
1 citations,
January 2018 in “Journal of Steroids & Hormonal Science” Oral vitamin D treatment can help some children with alopecia areata who have vitamin D deficiency.
1 citations,
January 2016 in “Journal of Nepal Paediatric Society” A child with rickets and hair loss might have a rare type of rickets that doesn't improve much with usual vitamin D and calcium treatment.
February 2022 in “Global academic journal of medical sciences” People with alopecia areata have much lower Vitamin-D levels than healthy individuals.
January 2022 in “International Journal of Medicine in Developing Countries” Many patients with hair loss had low iron and vitamin D levels, but thyroid issues were not common.
February 2018 in “Egyptian Journal of Radiation Sciences and Applications” Patients with Discoid Lupus Erythematosus have lower vitamin D and antioxidant levels and higher oxidative stress.
July 2021 in “PARIPEX INDIAN JOURNAL OF RESEARCH” Men with early baldness often have low vitamin D levels.
October 2023 in “Benha Journal of Applied Sciences” Methotrexate and vitamin D3 are potentially more effective and safer than triamcinolone for treating localized alopecia areata.
48 citations,
January 2015 in “Indian Journal of Dermatology, Venereology and Leprology” Vitamin D is important for skin health and can help treat psoriasis, atopic dermatitis, and vitiligo.
September 2023 in “International Journal of Trichology” Oral Vitamin D can improve hair density and reduce hair loss in Telogen Effluvium patients.
180 citations,
January 2002 in “The journal of investigative dermatology/Journal of investigative dermatology” Vitamin D Receptor is crucial for normal skin and hair growth.
20 citations,
January 2019 in “International journal of trichology” People with Alopecia areata often have lower Vitamin D levels, which might affect the severity of their condition.
13 citations,
April 1994 in “Baillière's clinical endocrinology and metabolism” Some people have genetic mutations that make them resistant to vitamin D, leading to rickets even with enough vitamin D intake.
7 citations,
January 2019 in “Indian dermatology online journal” People with alopecia areata often have lower vitamin D levels, which may be linked to the condition's severity.
5 citations,
July 2017 in “International journal of endocrinology and metabolism/International journal of endocrinology and metabolism.” Two siblings with a genetic mutation had a form of rickets that doesn't respond to vitamin D.
4 citations,
April 2020 in “Journal of Cosmetic Dermatology” Low vitamin D levels are linked to different types of hair loss.
1 citations,
January 2019 in “Indian journal of paediatric dermatology” Kids with alopecia areata had lower vitamin D levels than healthy kids.
March 2024 in “Skin research and technology” High CRP levels could indicate vitamin D deficiency in people with alopecia areata.
January 2019 in “Egyptian Journal of Dermatology and Venereology /Egyptian Journal of Dermatology and Venerology” Low vitamin D levels might indicate more severe hair loss in alopecia areata patients.
151 citations,
June 2010 in “Endocrinology and metabolism clinics of North America” Two rare genetic diseases cause severe rickets in children due to defects in vitamin D metabolism.
139 citations,
September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” Mutations in the Vitamin D receptor gene can cause hair loss similar to mutations in the Hairless gene.
107 citations,
March 2014 in “BoneKEy Reports” Mutations in the vitamin D receptor cause hereditary vitamin D-resistant rickets, leading to poor bone health and requiring high calcium doses for treatment.
22 citations,
November 2016 in “International journal of molecular sciences” Vitamin D receptor is important for regulating hair growth and wound healing in mice.