March 2026 in “International Journal of Molecular Sciences” This study found that Grateloupia angusta extract improved wound healing by promoting matrix production and pro-angiogenic activity in cell cultures and enhanced early wound repair in a mouse skin incision model.
110 citations
,
January 1995 in “European Journal of Neuroscience” This study found that glycinergic synapses in the rat spinal cord are predominantly associated with gephyrin, though gephyrin may also be present at non-glycinergic synapses.
This study successfully established a functionally stable immortalized sheep granulosa cell line (GCs-SV40T-GFP) that can passaged up to 50 generations, maintaining morphological stability and estradiol secretion, offering a valuable model for research into animal reproductive function and hormone regulation.
This theoretical research project proposes the Carnivore Follicular Integrity Framework, suggesting that animal-based diets may support hair follicle stability through various evolutionary and mechanistic pathways.
3 citations
,
December 2020 in “Journal of the turkish academy of dermatology” This study concluded that stromal vascular fraction treatment was effective in increasing hair density and thickness in patients with androgenetic alopecia over a three-month period.
8 citations
,
May 2024 in “PLoS Biology” This study on feather pattern formation in chicken skin found that inhibiting gap junctional intercellular communication can lead to the emergence of new feather buds in specific spatial patterns, suggesting that GJIC may facilitate Turing-type periodic patterning by propagating inhibitory signals over long distances.
7 citations
,
February 2015 in “Journal of comparative pathology” This study observed that NSG-hu-BLT mice developed graft-versus-host disease characterized by CD8+ T lymphocyte-related cell death in the skin and liver, which may affect their utility in other research areas.
39 citations
,
January 2020 in “Frontiers in Genetics” This study found that stage-specific epigenetic changes, particularly involving the gene PDGFC, may affect wool fiber development in Zhongwei goats, potentially serving as a biomarker for fur goat selection.
September 2025 in “ACS Applied Materials & Interfaces” The researchers reported that a newly developed photo-cross-linked hydrogel with multifunctional properties, including antimicrobial and antioxidant effects, significantly improved diabetic wound healing, achieving over 90% wound closure in seven days in vivo.
2 citations
,
March 2023 in “European Polymer Journal” This study developed multifunctional nanofiber wound dressings that significantly reduced bacteria and promoted healing in a mouse wound model by incorporating antibacterial and growth-promoting agents.
44 citations
,
September 2019 in “The EMBO Journal” This study found that lymphatic vessels in mice are important for hair follicle development and organization, as their depletion blocks hair growth.
7 citations
,
June 2020 in “npj regenerative medicine” This study found that GDNF promotes hair formation and skin wound repair by enhancing the self-renewal and differentiation of bulge stem cells in mice.
137 citations
,
December 2007 in “Journal of bone and mineral research” This study suggests that 1,25-dihydroxyvitamin D(3) and fibroblast growth factor 23 form a crucial axis in regulating phosphate balance, akin to its role in calcium regulation, and explores novel VDR interactions including with curcumin.
2 citations
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September 2020 in “International Journal of Molecular Sciences” In this study, the elimination of NG2+ hair follicle stem cells during the anagen phase was associated with an aggravated sensitization phase of allergic contact dermatitis, suggesting their immunosuppressive role.
47 citations
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May 1995 in “Journal of Investigative Dermatology” Hair follicles in people with alopecia have lower levels of a key blood vessel growth protein.
April 2026 in “International Journal of Current Pharmaceutical Review and Research” This study concluded that Growth Factor Concentrate was more effective than Platelet-Rich Plasma in enhancing hair growth and patient satisfaction for individuals with androgenic alopecia and telogen effluvium, while maintaining similar safety.
July 2024 in “Journal of Investigative Dermatology” JW0061 may be a new treatment for hair loss by promoting hair growth through WNT signaling.
31 citations
,
February 2014 in “Journal of dermatological science” This study found that placental growth factor (PlGF) enhanced hair shaft elongation and accelerated hair follicle growth, suggesting its potential as a therapeutic target for alopecia.
August 2022 in “Italian Journal of Animal Science/Italian journal of animal science” This study found that supplementing Angora goats with whole field bean seeds postpartum did not prevent weight and body condition losses but was associated with improved mohair growth and kid weight gain, likely due to better nutrient partitioning towards lactation and hair growth.
50 citations
,
February 2013 in “BMC evolutionary biology” This study found that the Hr gene loss and positive selection for the FGF5 gene in cetaceans likely contributed to hair loss as these animals adapted to aquatic environments.
11 citations
,
August 2021 in “Stem Cell Research & Therapy” This study reports that a single transplantation of autologous stromal vascular fraction significantly increased hair density and keratin score in androgenic alopecia patients within six months.
June 2023 in “JAAD case reports” This case report describes a 39-year-old female with cutis verticis gyrata and cicatricial alopecia, emphasizing the need for further understanding of the potential genetic associations and underlying mechanisms.
68 citations
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February 1996 in “Obesity Surgery” This study found that significant hair loss in about one-third of patients after vertical gastroplasty was reversed by zinc supplementation.
1 citations
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October 2025 in “Frontiers in Bioengineering and Biotechnology” This study developed a multifunctional bilayer dressing containing nanosilver and basic fibroblast growth factor, which improved wound healing by preventing bacterial penetration, promoting angiogenesis and hemostasis, and accelerating cell proliferation and migration, outperforming a control group by increasing healing rates by 47% in vivo.
1 citations
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December 2020 in “Case reports in dermatological medicine” This case report discusses a 67-year-old male with pre-existing pemphigus vulgaris who showed nearly 90% resolution of his skin lesions after two weeks of acyclovir treatment, accompanied by continued use of systemic steroids.
7 citations
,
March 2022 in “International Journal of Molecular Sciences” This study found that FGF21 suppresses inflammation induced by C. acnes in both human skin cells and mouse models, suggesting potential use in acne treatment.
109 citations
,
April 1998 in “Journal of Investigative Dermatology” This study found that recombinant human HGF/SF injections altered hair follicle growth cycles and mildly promoted hair elongation in mice, depending on their hair cycle stage.
April 2018 in “Journal of Investigative Dermatology” This study found that high skin expression of amphiregulin in acute graft-versus-host disease was associated with severe disease grade, poor overall survival, and increased non-relapse mortality.
October 2024 in “OBM Transplantation” In this case study, a patient with moderate papulopustular acne showed improvement in acne scars and active lesions after three monthly treatments with autologous plasma-rich growth factors, which help regulate inflammation, inhibit bacterial growth, and restore collagen.
18 citations
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June 2017 in “Proceedings of the National Academy of Sciences of the United States of America” In this mouse study, hair growth defects associated with the Gk5 null allele were partially alleviated by simvastatin treatment, suggesting GK5 plays a key role in skin-specific cholesterol regulation.