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This study found that the absence of vitamin D receptor-mediated suppression of PPARγ expression causes hair loss in VDR-null mice.

This study found that the 15-PGDH inhibitor DPP improved endothelial function in hair-related cells exposed to DHT by reducing oxidative stress and enhancing angiogenic capacity.

This study found that young adults, particularly females, experiencing diffuse hair fall had significantly lower Vitamin D3 levels compared to their age-matched healthy counterparts.

This study found that vitamin D deficiency in patients with alopecia areata was associated with greater disease severity and longer duration, but not with disease pattern or vitamin D receptor expression.

This study found that intracrine androgen signaling, mediated by steroid 5α-reductase, is essential for optimal decidualization and vascular development in the endometrium during pregnancy, indicating potential targets for improving age-related fertility issues.

This study developed a dissolvable microneedle system delivering specific molecules to remodel lymphatic networks and normalize metabolic processes, which accelerated hair growth and activated hair follicle stem cells in a mouse model of androgenetic alopecia.

In this interventional therapeutic study, both intralesional triamcinolone acetonide and vitamin D3 showed significant improvement in alopecia areata, with terminal regrowth more frequently observed in the steroid group, although differences were not statistically significant.

This study found that in participants with notalgia paresthetica, 8 weeks of treatment with difelikefalin significantly improved itch intensity and increased the rate of strict complete response compared to placebo, starting as early as week 3.

This study found that extracellular vesicles derived from 3D cultures of cervical cancer cells have small RNA profiles more similar to those in patient plasma than those from 2D cultures.

In this study, researchers developed an AI-powered platform called VitaDetect, which screens for vitamin deficiencies using image analysis of nails, tongue, and skin, aiming to provide an accessible and early-stage detection tool in resource-limited settings.

This study found that dracorhodin perchlorate improved wound healing in diabetic rats by regulating the TLR4 pathway and related inflammatory factors.

This study found that among vitiligo patients in south-southern Nigeria, there were significant correlations between digit lengths and digit ratio, but further research is needed due to the small sample size.

This study found that patients with seborrheic dermatitis were more likely to have severe vitamin D deficiency compared to healthy controls.

This study reported that the combination of a 308-nm excimer lamp and 10% liquor carbonis detergens significantly improved scalp psoriasis symptoms compared to the excimer lamp alone, with more patients achieving 75% reduction in their Psoriasis Scalp Severity Index.

This study found that nanobubble-encapsulated diclofenac with ultrasound-targeted microbubble destruction (DNBs-UTMD) can enhance the anti-tumor efficacy of Doxil® by regulating the tumor immune microenvironment, improving drug uptake, and increasing T cell responses while reducing immune-suppressive cells in the process.

This study observed that cultured dermal papilla cells showed distinct functional properties from dermal fibroblasts, including lower proliferation rates, higher adhesion to collagen type IV, and different cell-matrix interactions.

This abstract highlights that preliminary results from the REDUCE trial indicate dutasteride may lower prostate cancer incidence by 23% in older men compared to a placebo.

This study found that videodermoscopy enhances diagnostic accuracy for scalp and hair disorders beyond simple clinical inspection and reveals novel disease features that could improve clinical understanding.

This study found that women with female pattern hair loss had significantly lower serum vitamin D levels than healthy controls, suggesting a possible role of vitamin D deficiency in the condition.

This study demonstrated that an LC/MS-MS method could effectively detect and quantify the vitamin B3 vitamer nicotinamide in human hair, suggesting its potential use for long-term deficiency examination.

This study examined 3D-printed scaffolds coated with polydopamine and observed that they significantly enhanced osteogenesis and angiogenesis in vitro and in a rat cranium defect model, suggesting their potential for repairing large bone defects.

This study found that intralesional Vitamin D3 injections were comparable in efficacy to intralesional triamcinolone for patchy alopecia areata, with a non-significant trend towards better outcomes and fewer local adverse effects.

This study concluded that the hairless protein interacts with the vitamin D receptor to repress transcription crucial for hair cycling, employing multiple protein interfaces and modulating chromatin structure.

This study presents two cases correlating the clinical appearance of adult-onset foveomacular vitelliform dystrophy with optical coherence tomography findings, describing the location of the yellow vitelliform material.

This study found that vitamin D receptor expression is associated with proliferating keratinocytes, while retinoid X receptor α is linked to differentiating keratinocytes, suggesting differential targeting by vitamin D metabolites.

This study found that mechanical disruption of the desmosomal cadherin Dsg3 in hair follicle stem cells activates them from quiescence, highlighting its role as a key regulator of stem cell quiescence and epithelial niche integrity.

In this retrospective case series, therapeutic responses to immunomodulatory and incretin-based therapies for Dercum's disease showed considerable individual variation, suggesting these treatments might be exploratory options when surgery isn't feasible, though further controlled studies are needed for definitive conclusions.

This study suggests that while vitamin D3 deficiency is linked to alopecia areata severity, evidence for the effectiveness of supplementation or topical calcipotriol treatment remains inconsistent and low quality.