Dracorhodin Perchlorate Regulates the Expression of Inflammatory Cytokines Through the TLR4 Pathway and Improves Skin Wound Healing in Diabetic Rats
April 2022
in “
Evidence-based Complementary and Alternative Medicine
”
TLDR Dracorhodin perchlorate helps heal wounds in diabetic rats by reducing inflammation.
The study found that Dracorhodin Perchlorate (DP) improved wound healing in diabetic rats by reducing inflammation and promoting angiogenesis through the TLR4 pathway. DP treatment decreased inflammatory cytokines, enhanced collagen deposition, and increased microvessel density, which are essential for tissue repair. The study concluded that DP could enhance wound healing in diabetic conditions by inhibiting excessive inflammation and promoting new blood vessel formation, suggesting its potential as a therapeutic target for diabetic wound healing. Further research was recommended to explore DP's effects on growth factors and oxidative stress.