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Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Keratin 15 is not a reliable sole marker for identifying epidermal stem cells because it's found in various cell types.

Choosing the right recall period for patient feedback is important for accurate data and depends on the disease, symptom changes, and patient impact.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Toxic Shock Syndrome progresses quickly, often involves multiple organs, and is linked to Staphylococcus aureus toxins, with treatment options available but diagnostic challenges remaining.

Treatment of acromegaly can improve women's reproductive health issues caused by hormonal imbalances or tumors.

Toxic epidermal necrolysis is a severe skin condition often caused by drugs, with complex treatment and a high risk of death, but survivors usually heal without scars.

Most dermatologic medications are safe during pregnancy and breastfeeding, but some should be avoided due to potential risks.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

New genes and pathways are important for testosterone production and male sexual development.

Tissue-resident memory T cells can protect against infections and cancer but may also contribute to autoimmune diseases.

Msx2 and Foxn1 are both crucial for hair growth and health.

Overexpressing the mineralocorticoid receptor in mouse skin causes skin thinning, early skin barrier development, eye issues, and hair loss.

Estrogens and SERMs can help with skin aging, but their safety and effectiveness need more research.

Fulvestrant is a well-tolerated new treatment for advanced breast cancer that may delay chemotherapy.

Lithium therapy may cause skin problems like hidradenitis suppurativa and other side effects, which can improve after stopping the medication.

Sub3 is essential for fungus adherence but not for skin invasion.

Finasteride effectively treats male pattern baldness, improving hair growth and density.

Notch-related genes play a key role in the development and cycling of hair follicles.

Immunosuppressive and anti-TNF therapies in IBD patients can increase the risk of skin cancer and cause various skin issues.

Products should be called 'sperm-safe' only after thorough, well-designed tests.

Graft-versus-host disease is a complication where donor immune cells attack the recipient's body, often affecting the skin, liver, and gastrointestinal tract.

Nanocarrier-loaded gels improve drug delivery for cancer, skin conditions, and hair loss.

Patients with Bohring-Opitz syndrome and ASXL1 mutations need regular kidney ultrasounds to check for tumors.

Some dermatological medications can impair male fertility, so consult a doctor before trying to conceive.

Antidepressants, 5α-reductase inhibitors, and isotretinoin can cause long-lasting sexual dysfunction.

Men with enlarged prostates often have more severe baldness.

Botulinum toxin shows promise for various skin conditions but requires more research for confirmation and standardized use.

Botox increased hair count in men with baldness and might work by improving scalp blood flow.

Early detection and treatment of PCOS in teenagers is important to manage symptoms and prevent severe issues.