March 2026 in “Cosmetics” In this comprehensive review, researchers reported that macromolecules like type I collagen, keratin, and ceramides enhance hair health by improving follicular function and increasing hair density, strength, shine, and resilience, as shown in various in vitro, animal, and human studies.
March 2026 in “Journal of the mechanical behavior of biomedical materials/Journal of mechanical behavior of biomedical materials” This study investigated the mechanical response of the human hair cuticle to strain and found that cuticular deformation directly corresponded with fiber elongation, revealing significant molecular-level changes in disulfide crosslinks but maintained structural stability, highlighting the role of the cuticle in stress resistance.
February 2026 in “iScience” This study found distinct hair metal profiles in Parkinson's disease patients, with lower iron and copper, higher manganese and arsenic, and explored their link to gut dysfunction and microbiota dysbiosis, suggesting hair metal analysis as a promising diagnostic tool.
December 2025 in “Biomolecules” This study reviews the emerging role of protein S-palmitoylation in dermatology, highlighting its impact on skin functions like inflammation and barrier maintenance, and evaluating its potential as a therapeutic target for skin disorders such as alopecia and psoriasis.
December 2025 in “Cosmetics” This review highlights that post-oncologic skin suffers from several impairments following cancer treatments, and dermocosmetic strategies, particularly those involving nanocarriers, can enhance the efficacy and stability of antioxidants, thereby aiding skin regeneration and improving quality of life.
November 2025 in “Biomedicines” This study found that the JAK1 inhibitors baricitinib and abrocitinib significantly reduced mechanical alloknesis in a murine model of atopic dermatitis, whereas the JAK2 inhibitor AZ960 had no effect.
August 2025 in “Nanomaterials” This study found that tea polyphenol–zinc significantly improved intestinal barrier function and reduced liver inflammation and oxidative stress in mice with diquat-induced damage.
August 2025 in “BMC Genomics” In this study, researchers found distinct gene expression patterns in Standardbred trotters capable of racing barefoot, suggesting a genetic basis for hoof strength and identifying specific genes involved in hoof biology, which could enhance equine performance and wellbeing through targeted genetic research.
August 2025 in “Applied Sciences” This study found that peroxide-rich plasma-activated water caused minimal morphological damage to hair, while nitrate-rich plasma-activated water induced significant damage, especially in porous hair types.
This preclinical study found that finasteride withdrawal in rats caused inflammation in the gut and hypothalamus, while allopregnanolone treatment partially reduced these effects, suggesting potential therapeutic benefits for post-finasteride syndrome.
July 2025 in “International Journal of Trichology” This source discusses the ethical dilemmas and business pressures in cosmetic dermatology, emphasizing the shift toward commercialism and profit-driven practices influenced by social media and market demands, potentially leading to conflicts of interest and professional misconduct.
January 2025 in “International Journal of Nanomedicine” In this study, a metformin-loaded rosemary-based nanoemulgel was found to significantly enhance hair follicle growth in rats, suggesting its potential as a new treatment for androgenetic alopecia due to its promising physicochemical properties and controlled drug release.
January 2025 in “Dermatologic Therapy” In this study, treatment with fractional CO2 laser combined with recombinant humanized type III collagen led to significantly better improvements in atrophic acne scars compared to laser treatment with saline, attributed to collagen upregulation and MAPK pathway activation in human dermal fibroblasts.
August 2024 in “Clinical Cosmetic and Investigational Dermatology” This report describes the successful resolution of an epidermoid cyst using a minimally invasive approach with intralesional injection of recombinant enzymes.
December 2021 in “Figshare” This study found that BBS7 is downregulated in occlusal hypofunctional periodontal ligament, suggesting it plays a crucial role in maintaining Shh signaling for PDL homeostasis.
4 citations
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February 2023 in “iScience” This study found that unique genomic regions in Korean long-tailed chickens may contribute to their long tail feathers, offering potential for genetic advancements in ornamental chicken breeding.
13 citations
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April 2016 in “Journal of Visualized Experiments” This study describes a method for isolating stem cells and keratinocytes from mouse hair follicles using FACS technology, facilitating the study of stem cell biology.
29 citations
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April 1995 in “Endocrinology” In this study, finasteride treatment did not negatively impact bone development or density in male rats, suggesting that DHT deficiency is not harmful to the male rat skeleton.
August 2007 in “Microscopy and Microanalysis” Hair fibers break by cuticle cell slipping, shape changing, cuticle fraying, and surface cracking when stretched under specific conditions.
132 citations
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January 2017 in “International Journal of Molecular Sciences” This review explores how adipose-derived stem cells contribute to skin homeostasis and highlights recent advances in their clinical applications in dermatology, but it reports no new clinical results.
29 citations
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December 2016 in “The EMBO Journal” This study found that the transcription factor Gata6 plays a crucial role in adult mouse hair follicle regeneration by promoting the renewal and preventing DNA damage of rapidly proliferating progenitor cells.
21 citations
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July 2006 in “Veterinary dermatology” In this study, researchers reported that CD34 expression in the isthmic region of canine hair follicles suggests a potential stem cell compartment in this area.
20 citations
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June 2010 in “Genes and Immunity” This study found distinct gene expression patterns in the blood of alopecia areata patients, suggesting involvement of immune processes and new pathways like Wnt signaling and apoptosis in disease pathogenesis.
6 citations
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September 2009 in “European journal of histochemistry” This study found that CD90+ stem cells with fibroblast-like morphology are present in the lower part of the anagen hair follicle in dogs.
5 citations
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January 2021 in “IEEE Access” In this study, researchers demonstrated that treating platelet rich plasma with microsecond pulsed electric fields effectively activates platelets and induces similar or higher growth factor release compared to traditional bovine thrombin, suggesting a potential clinical use that may be more cost-effective and practical.
4 citations
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April 2002 in “Medical Hypotheses” Hormones cause hair loss by affecting cell growth and weakening cell attraction.
41 citations
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August 2024 in “Drug Delivery and Translational Research” This review discusses the development and applications of microneedles, particularly through 3D printing, highlighting their potential in transdermal drug delivery but reporting no new results.
31 citations
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January 2014 in “Journal of endocrinological investigation” This study reviewed Woodhouse-Sakati syndrome and found it consistently associated with hypogonadism, decreased IGF1, and frontotemporal alopecia, with additional symptoms like intellectual disabilities and diabetes in some patients.
28 citations
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December 2013 in “British Journal of Oral & Maxillofacial Surgery” This article reviews age-related changes in facial structure at a cellular level and summarizes potential solutions for rejuvenation surgery, but reports no new clinical results.
23 citations
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December 2001 in “Lasers in Surgery and Medicine” This article discusses the extended theory of selective photothermolysis and does not report new clinical results; the authors explore potential applications in hair removal techniques.