August 2022 in “Frontiers in Pharmacology” Ultrasound can improve targeted drug delivery, making treatments more effective with fewer side effects.
14 citations
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February 2021 in “Journal of the European Academy of Dermatology and Venereology” This article reports a case of rapidly progressive alopecia areata totalis in a COVID-19 patient that did not respond to treatment with tofacitinib; no new clinical results are discussed.
This case report describes a 41-year-old man with preauricular and postauricular plaques unresponsive to topical treatments, with lab results indicating low-titer antibodies for Sjögren syndrome A and B.
16 citations
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November 2008 in “Journal of the American Academy of Dermatology” This case report describes a patient with a hepatitis C diagnosis whose acral rash, initially unresponsive to psoriasis treatment, showed significant improvement with oral zinc sulfate, suggesting a diagnosis of necrolytic acral erythema.
February 2026 in “Frontiers in Pharmacology” This study found that injecting PRP gel derived from a patient's own blood may promote tissue regeneration and closure of intestinal fistulas unresponsive to conservative therapy.
January 2024 in “International Journal of Homoeopathic Sciences” In this case study, a 29-year-old woman's acne scars improved alongside enhancements in emotional well-being following six months of personalized homeopathic treatment, suggesting potential benefits for individuals unresponsive to conventional therapies, though further research is needed to substantiate these findings.
8 citations
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January 2016 in “Case Reports in Psychiatry” The authors report a dementia patient who developed severe trichotillomania unresponsive to SSRIs, which improved with quetiapine; they suggest dopamine blockade may manage such symptoms in dementia.
6 citations
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July 2015 in “JAAD Case Reports” This study describes a case of erlotinib-induced alopecia, unresponsive to traditional corticosteroid treatments, that was successfully managed with doxycycline, suggesting a novel approach for EGFR inhibitor-associated alopecia.
5 citations
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January 2018 in “Skin appendage disorders” Minoxidil base is preferred for hair loss treatment, but minoxidil sulfate may be an alternative for unresponsive patients.
1 citations
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January 2013 in “Annals of Dermatology” This case report describes an 11-year-old girl with eosinophilic pustular folliculitis that showed significant improvement with naproxen after being unresponsive to other treatments.
May 2025 in “Orphanet Journal of Rare Diseases” This review suggests that immunomodulators, including TNF-α blockers and IL inhibitors, may improve symptoms of moderate-to-severe dissecting cellulitis of the scalp, but their effects on hair regrowth and scarring remain unclear.
July 2026 in “International Journal of Homoeopathic Sciences” This case study reported complete hair regrowth in a 29-year-old female with alopecia areata after individualized homeopathic treatment, which included Pulsatilla, Fluoric Acid, and Syphilinum, following unsuccessful allopathic and Ayurvedic therapies.
17 citations
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October 2006 in “Molecular and Cellular Endocrinology” This study found that the L457(3.43)R mutation in the human luteinizing hormone receptor increases phosphodiesterase activity, reducing hormonal response despite elevated basal cAMP levels.
25 citations
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March 2017 in “International Journal of Dermatology” In this case report, two women with chronic alopecia areata and acute alopecia universalis experienced sustained and near-complete hair regrowth after over a year of treatment with oral ruxolitinib, without significant side effects.
February 2026 in “Cureus” This case report suggests that crisaborole may be an effective alternative treatment for alopecia areata in pediatric patients, showing significant hair regrowth after two weeks in a 10-year-old girl.
May 2026 in “Frontiers in Immunology” This case report documents the first use of bimekizumab as monotherapy for dissecting cellulitis of the scalp, where a 27-year-old man experienced significant symptom relief without adverse effects after failing standard treatments.
January 2026 in “Figshare” In this case report, the researchers documented two instances of melasma linked to finasteride use, highlighting the need for clinicians to review medication history when treating facial hyperpigmentation, especially in individuals with darker skin types.
January 2019 in “Cell & developmental biology” This study found that using 3D cultures and fetal tissue extracts significantly improved the outcomes of stem cell treatments for regenerative medicine, including hair follicle formation and chronic wound healing.
17 citations
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July 2024 in “Frontiers in Oncology” This review discusses recent advances in understanding Merkel cell carcinoma biology, including the development of genetically-engineered mouse models and potential therapeutic targets, but reports no new clinical results.
5 citations
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March 2023 in “PubMed” This review discusses the potential of advanced therapy medicinal products for treating vitiligo, highlighting promising results but noting affordability remains a challenge; no new clinical results were reported.
1 citations
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May 2025 in “Frontiers in Medicine” In this case series, dual-targeted therapy was observed to provide promising clinical responses in refractory inflammatory bowel disease, with 88.23% to 100% response rates across 9 months and an endoscopic response in 88.89% of evaluated patients, though some adverse events occurred.
January 2026 in “Frontiers in Pharmacology” This review reports that topical minoxidil remains the primary treatment for androgenetic alopecia, while oral and sublingual forms offer alternative options, each with varying efficacy and side effects.
January 2016 in “China Medical Abstracts(Dermatology)” This article outlines diagnosis and treatment guidelines for androgenetic alopecia but reports no new clinical findings.
26 citations
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April 2024 in “Particle and Fibre Toxicology” In this study, researchers investigated the penetration and cellular responses to nanoplastics in human skin models with compromised barriers, finding that nanoplastics can penetrate the skin, accumulate in cells, and trigger inflammatory responses through specific signaling pathways.
8 citations
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November 2011 in “Journal of Medical Case Reports” This case report describes a 23-year-old Asian woman with fluoxetine non-responsive trichotillomania who showed significant improvement with bupropion and cognitive behavior therapy, though confirmation in larger trials is needed.
115 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” In this study, PRP injections increased hair count and reduced hair loss in patients with androgenic alopecia not responding to minoxidil and finasteride, with high patient satisfaction reported.
38 citations
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March 2019 in “International Wound Journal” In this study, a new cell-tissue technology using a patient's own skin to create a full-thickness skin autograft successfully treated a chronic wound larger than 200 cm², achieving complete functional skin coverage within 12 weeks and maintaining results at a 6-month follow-up.
2 citations
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February 2021 in “Case reports in dermatological medicine” In this case series, the topical botanical formulation GASHEE demonstrated significant improvements in hair regrowth without adverse events among patients with hair loss, including cases where previous treatments had failed.
31 citations
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June 2011 in “Movement Disorders” The document describes a woman with familial Parkinson's disease due to a genetic mutation, showing severe symptoms and poor response to treatment, and suggests finasteride may help reduce symptoms in Tourette syndrome.
6 citations
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February 2017 in “Case Reports in Dermatology” This case report highlights that hair loss, though common in the general population, may be a rare presenting symptom of Cushing's disease, as observed in a woman with multiple dermatological signs of the condition.