19 citations,
March 1990 in “Journal of Cardiovascular Pharmacology” Minoxidil affects rat fluid dynamics, altering pressure and circulation, improving blood flow and hair growth.
15 citations,
June 1995 in “The American Journal of the Medical Sciences” Finasteride caused enlarged breast tissue in a 62-year-old man.
14 citations,
February 2018 in “Psychoneuroendocrinology” Mice lacking steroid 5α-reductase 2 show less aggression and better impulse control.
14 citations,
September 2015 in “Expert Opinion on Therapeutic Targets” The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
13 citations,
April 2009 in “Acta Medica Scandinavica” Minoxidil lowers blood pressure and causes hair growth, with some side effects.
13 citations,
May 1996 in “Archives of Disease in Childhood” Siblings with signs of virilization should be tested for non-classical congenital adrenal hyperplasia, which does not affect adult height but may impact fertility and well-being if untreated.
11 citations,
December 2018 in “Assay and Drug Development Technologies” Natural herbal compounds might treat certain medical conditions by reducing DHT levels, but more research is needed to confirm their effectiveness and safety.
11 citations,
February 2018 in “Amino acids” Copper and iron cause keratin damage in hair by converting methionine to homocysteine.
11 citations,
February 2016 in “Current Medicinal Chemistry” New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.
10 citations,
February 2020 in “Endocrine” Finasteride safely treats hair loss without harming hormones or reproduction, but may slightly reduce sexual function.
10 citations,
May 2018 in “Cell death discovery” HSP90 and lamin A/C are crucial for hair growth and could be targets for treating hair loss.
10 citations,
March 2015 in “American journal of primatology” Ingesting Leucaena leucocephala caused hair loss and increased infant mortality in ringtailed lemurs.
10 citations,
June 2011 in “Archives of Dermatology” Finasteride caused blisters on hands and feet.
10 citations,
January 2003 in “Seminars in reproductive medicine” The article explains how to identify and treat excessive hair growth in women, which can be distressing and may signal other health problems.
9 citations,
January 1997 in “Gynecological Endocrinology” The document concludes that treating androgen excess needs patience, managing expectations is important, and many drugs used are not officially approved, suggesting cosmetic options for mild cases.
8 citations,
July 2019 in “Endocrine connections” Finasteride affects SRD5A2 gene pattern, possibly causing lasting side effects.
8 citations,
May 2019 in “Journal of dermatological treatment” Vismodegib is effective for basal cell carcinoma but has severe side effects.
8 citations,
June 2016 in “Journal of Pharmacy Practice” Lisinopril, a heart medication, probably caused hair loss in a patient, which stopped after switching drugs.
6 citations,
October 2017 Indian Gooseberry has potential for cancer prevention and treatment and promotes hair growth.
6 citations,
April 2014 in “European journal of medicinal chemistry” New compounds similar to cromakalim were less effective at inhibiting insulin release but improved in solubility and one acted as a calcium entry blocker, not a potassium channel opener.
5 citations,
May 2023 in “Frontiers in immunology” Environmental factors like diet and vitamin levels, especially Vitamin D, can affect autoimmune diseases differently, with lifestyle changes potentially improving outcomes.
4 citations,
November 2023 in “Frontiers in immunology” New treatments targeting T-cell pathways are needed for better alopecia areata management.
4 citations,
January 2015 in “Journal of microbial & biochemical technology” Biotin helps regulate proteins in the blood, which may explain its role in hair growth.
3 citations,
April 2021 in “Journal of Medicinal Chemistry” Finasteride may affect PNMT, causing side effects.
3 citations,
November 2018 in “Journal of cellular physiology” Serenoa repens and N-acetyl glucosamine/milk proteins complex may help with hair growth and prevent hair loss.
3 citations,
January 2017 in “Revista chilena de nutrición” Certain natural compounds called terpenes may help prevent prostate cancer.
3 citations,
February 2016 in “Scandinavian journal of urology” Finasteride use varies among Denmark, Finland, Norway, and Sweden, with higher usage in Finland and Sweden.
2 citations,
January 2015 in “Springer eBooks” Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.
2 citations,
July 2014 in “Irish Journal of Medical Science” The meeting discussed medical findings, including benefits of certain treatments for cancer and heart conditions, and highlighted issues like poor adherence to preventive measures and skill gaps among interns.
2 citations,
November 2011 in “InTech eBooks” Most adrenal cortex tumors are benign and non-secreting, but proper diagnosis and treatment are important due to the rare possibility of cancer.