research Androgen Biosynthesis and Gene Defects
Gene mutations can cause problems in male genital development.
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research Anti-Androgens for the Treatment of Hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.
research Development of Optimized Self-Nanoemulsifying Lyophilized Tablets to Improve Finasteride Clinical Pharmacokinetic Behavior
Improved tablets lead to faster, better drug absorption for hair loss treatment.
research The Anti-Androgen Combination, Flutamide Plus Finasteride, Paradoxically Suppressed LH and Androgen Concentrations in Pregnant Spotted Hyenas, but Not in Males
Flutamide and finasteride reduced sex hormones in pregnant hyenas, but increased them in males.
research Polycystic Ovary Syndrome: Anogenital Distance as a Marker of Prenatal Androgenic Environment and Review and Comparison of Diagnostic Criteria
Longer anogenital distance may indicate a higher chance of having polycystic ovary syndrome, and measuring this distance along with hormone levels could improve diagnosis.
research Depth and Patterns of Adnexal Involvement in Primary Extramammary (Anogenital) Paget Disease: A Study of 178 Lesions From 146 Patients
Extramammary Paget disease can spread deeply into tissues, reaching up to 3.6 mm.
research Single-Stage Dorsal Inlay Split-Skin Graft for Salvage Anterior Urethral Reconstruction
Split-thickness skin grafts are a good alternative for urethral reconstruction when buccal grafts can't be used.
research Involvement of Activation of Mitogen-Activated Protein Kinase (MAPK)/Extracellular Signal-Regulated Kinase (ERK) Signaling Pathway in Proliferation of Urethral Plate Fibroblasts in Finasteride-Induced Rat Hypospadias
The MAPK/ERK pathway is crucial in controlling cell growth and death in finasteride-induced hypospadias.
research Overview of Urethral Reconstruction by Tissue Engineering: Current Strategies, Clinical Status, and Future Direction
The best method for urethral reconstruction is using hypoxia-preconditioned stem cells with autologous cells on a vascularized synthetic scaffold.
research A New Method To Facilitate Complicated Urethral Catheterization In Men: A Technical Point Of View
A new method using a Foley catheter on a ureteroscope makes difficult urethral catheterization easier and more effective.
research Case Report: Penile Strangulation Secondary to Hair Tourniquet
Penile strangulation from hair can cause severe harm but can be treated if caught early.
research Partial Penile Amputation Due to Penile Tourniquet Syndrome in a Child With Primary Nocturnal Enuresis: A Rare Emergency
An 8-year-old boy with bed-wetting issues suffered a severe penile injury from tying a thread around his penis, requiring urgent medical treatment to avoid worse outcomes.
research Case Report: Disorder of Sex Development 46, XY with Proximal Hypospadias in a 10-Year-Old Twin Boy
A 10-year-old boy with abnormal genital development had surgery and tests to find the cause and plan treatment.
research Laser Hair Removal for Genital Gender Affirming Surgery
Laser hair removal before genital surgery can prevent complications and improve patient satisfaction.
research Histopathological Evaluation of Urethroplasty with Buccal Mucosa Graft: An Experimental Study in Rabbits
Buccal mucosa grafts work well for urethroplasty in rabbits.
research Adverse Drug Reactions and Interactions: Case Studies
Some medications caused temporary health issues that improved after stopping the drugs, but two patients died from liver problems linked to carbamazepine.
research Many Sexual Adverse Effects of Finasteride Are Attributable to a Nocebo Effect
Finasteride's sexual side effects may be due to nocebo effect.
research Congenital Adrenal Hyperplasia: Comprehensive Overview and Clinical Management
The document concludes that proper diagnosis and a multidisciplinary approach are crucial for managing Congenital Adrenal Hyperplasia effectively.
research Non-Classic Congenital Adrenal Hyperplasia
Non-classic congenital adrenal hyperplasia is a common disorder causing symptoms like acne and infertility, and it's managed based on symptoms, not just test results. Treatment can improve fertility and reduce miscarriage risk.
research Hair Removal Using an Nd:YAG Laser System
Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.
research Surgical Atlas: Primary Hypospadias Repair with Buccal Mucosa
Using buccal mucosa for hypospadias repair in children is effective and reduces complications.
research A Novel Mutation in the FERMT1 Gene in a Spanish Family with Kindler’s Syndrome
Researchers found a new mutation in the FERMT1 gene in a Spanish family with Kindler syndrome.
research Hair Coil Penile Tourniquet Syndrome in an Unusual Age
An 8-year-old boy recovered from a rare case of penile tourniquet syndrome after hair removal surgery.
research 5-Alpha-Reductase Deficiency in a Saudi Girl
A Saudi individual initially identified as a girl had a genetic disorder affecting gender development.
research Dimorphic Regulation of the MafB Gene by Sex Steroids in Hamsters (Mesocricetus Auratus)
Sex steroids affect the MafB gene differently in male and female hamsters.
research Preoperative Hormonal Stimulation in Hypospadias: A Systematic Review
Hormone treatment before hypospadias surgery can increase penis size and reduce surgery complications.
research The Distribution of Preputial Vessels in Different Severity of Rat Congenital Hypospadias Model: Imaging Study Using Micro-Computerized Tomography
The junction of the inner and outer prepuce with good blood flow is best for vascular pedicle flaps.
research The Distribution of Preputial Vessels at Different Severity of Rat Congenital Hypospadias Model
Micro-CT helps identify suitable areas for surgical procedures based on blood vessel distribution in hypospadias-affected rats.
research Proteomics Characterization of Primary Human Oral Epithelial Cells Using a Novel Culture Technique for Tissue Regeneration
ePUKs could be valuable for regenerative medicine due to their wound healing abilities.
research A Focus on Important Reproductive Health Care Issues – Cancer, Urinary Incontinence and the Consequences of Pre-Term Birth
The issue covers reproductive health topics like cancer markers, incontinence treatments, and the impact of pre-term birth.