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The guideline provides healthcare professionals in South Africa with instructions for comprehensive, multidisciplinary gender-affirming care, including HIV prevention and treatment for transgender and gender diverse individuals.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Nd:YAG laser can reduce hair with multiple treatments, but permanent removal isn't guaranteed.

Laser hair removal before genital surgery can prevent complications and improve patient satisfaction.

The document concludes that sex hormones and related compounds have various effects on health, with both potential benefits and risks.

Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.

Platelet-rich plasma shows promise for treating various female reproductive health issues but requires more research.

Improved understanding of stem cell mechanisms can enhance skin tissue engineering.

Finasteride treats enlarged prostate, shrinks it, improves urination, but may cause sexual dysfunction and isn't for women or children.

Skin symptoms are important for diagnosing infections in children.

Scalp expansion is an effective way to reconstruct the scalp with good cosmetic outcomes.

Pica disorder in central Iraq is mainly found in females and is linked to low iron levels; treatment with iron improves most patients.

Gynecologists should provide comprehensive care for transgender patients, including mental health evaluation, hormone therapy, and surgical options, while monitoring for side effects and ensuring patient safety.

Laser hair removal works well for people with dark hair and light skin, but it's less effective for light hair or dark skin; improvements are expected.

Silver can help prevent and treat infections but its effectiveness varies and should be weighed against costs and side effects.

Older adults still engage in sexual activities but face challenges like health issues and lack of professional support, highlighting the need for better healthcare provider education and research on sexual fulfillment in old age.

Injectables can feminize or masculinize a transgender person's face, but more research is needed for best practices.

Hair follicles are valuable for regenerative medicine and wound healing.

Obesity leads to physical, metabolic, reproductive issues, higher healthcare costs, and mental health problems.

Environmental factors and exposure to toxins may contribute to male infertility by affecting sperm and hormone function.

HNG may help prevent the negative effects of chemotherapy on sperm production and white blood cell counts.

Hormone therapy affects hair growth in transgender individuals, with testosterone potentially causing hair loss in trans men and estrogen reducing facial/body hair in trans women; treatment options vary.

Menopause reduces skin collagen and elasticity, and while estrogen therapy can help, its risks require careful consideration.

Menopause and aging can affect women's quality of life and sexuality, but hormone therapies may help alleviate these issues.

Non-hormonal treatments should be used first for sexual dysfunction in postmenopausal breast cancer patients on aromatase inhibitors, with hormones as a second option.

With careful management, people with congenital adrenal hyperplasia can have successful pregnancies and become parents.

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.

Hair follicle pores help cell survival and growth, even after radiation.