January 2024 in “Theranostics” This study found that hypoxia-preconditioned HF-MSC-derived exosomes improved therapeutic outcomes in models of ulcerative colitis, potentially through miR-214-3p-mediated pathways affecting mitochondrial function and inflammatory responses.
209 citations
,
March 1989 in “Journal of The American Academy of Dermatology” This study found that recombinant human leukocyte interferon alfa-2a achieved a 64% overall antitumor response rate in patients with early and advanced cutaneous T cell lymphoma and was generally well-tolerated.
18 citations
,
April 2010 in “Archives of Dermatology” This case report describes a patient with psoriasis and alopecia universalis where psoriasis plaques supported hair growth, suggesting cytokine interaction may influence competing immune responses.
10 citations
,
January 2020 in “Journal of Materials Chemistry B” This study developed a biodegradable nanofibrous biofilm that attracts skin-related cells and accelerates blood vessel formation, potentially improving skin wound healing.
July 2026 in “Nature Communications” This study used spatial transcriptomics to investigate T cell-hair follicle interactions in cutaneous lupus erythematosus across mice, dogs, and humans, finding that CXCR3+ T cells and B cells are enriched in lesional skin, with implications for potential therapeutic targets.
January 1994 in “European Journal of Cancer” The European School of Oncology organized various educational events in 1994, highlighting important cancer research findings.
November 2025 in “The Journal of Immunology” This study observed that in human scalp hair follicles, BTNL2 expression is lower in stressed conditions, which correlates with increased cytotoxic activity by gamma/delta and CD8+ T cells, suggesting a possible role for BTNL2 in controlling immune responses relevant to alopecia areata.
This report presents a rare case of lichen spinulosus in a 52-year-old woman, featuring hyperkeratotic follicular papules and a dense lymphohistiocytic infiltrate in affected skin areas.
22 citations
,
July 1998 in “Journal of Investigative Dermatology” This study identified and characterized a gene called 4C32, which is expressed in the periderm of embryonic mouse skin and has a structure similar to keratin-associated proteins.
5 citations
,
March 2016 in “Experimental and molecular pathology” In mouse models of alopecia areata, this study found increased dilation of lymphatic vessels in affected mice, with associated changes in gene expression related to vascular growth and immune cell movement.
1 citations
,
July 2024 in “Australasian Journal of Ultrasound in Medicine” In this study, researchers reported that cutaneous ultrasound may be a valuable tool in diagnosing and assessing inflammatory activity in tinea capitis, potentially guiding treatment decisions, especially in severe cases not apparent through clinical symptoms alone.
65 citations
,
February 2018 in “The Plant Journal” This study found that PLDζ2 and NPC4 enzymes play distinct roles in lipid remodeling and root hair growth in Arabidopsis under phosphate deficiency, influencing root hair density and length in a tissue- and time-specific manner.
1 citations
,
July 2022 in “PLOS ONE” This study found that in Lichen Planopilaris, the Microbacteriaceae family was negatively correlated with IL-23 expression, suggesting a role in the disease's inflammation and microbiota composition.
36 citations
,
March 2009 in “Molecular Carcinogenesis” This study found that Bcl-xL deficiency in mice increased apoptosis and resistance to skin tumor development, highlighting Bcl-xL's role in early skin carcinogenesis through anti-apoptotic functions.
1 citations
,
June 2022 in “Zenodo (CERN European Organization for Nuclear Research)” This study reports a rare case of alopecia areata on the scalp that was successfully treated with Sunetics Laser therapy, resulting in hair regrowth and repigmentation in areas of previous hair loss.
February 2016 in “Acta Medica Marisiensis” This case study presents what is reportedly the first association of Graham Little-Lassueur Syndrome with chronic hepatitis C, observed in a 47-year-old female patient.
503 citations
,
May 2009 in “Cell stem cell” This study suggests that Lrig1-positive cells form a previously unknown reservoir of interfollicular epidermal stem cells in adult mouse skin, influencing epidermal proliferation and hair follicle development.
5 citations
,
January 2010 in “International journal of trichology” This report describes two cases of alopecia totalis treated with turban psoralen and sunlight exposure, but it provides no clinical outcome results.
16 citations
,
January 2020 in “Annals of the rheumatic diseases” In this study, baricitinib improved the resolution of arthritis or rash in patients with systemic lupus erythematosus, but outcomes for skin involvement like alopecia were not reported.
March 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” This study suggests that the expression of VLCFA biosynthesis genes is suppressed in skin hyperplasia and cancer, which could influence keratinocyte function.
50 citations
,
February 2004 in “Genomics” This study identified a missense mutation in the rat Desmoglein 4 gene, causing abnormal hair shaft development in lanceolate hair mutant rats by disrupting a critical calcium binding site.
4 citations
,
May 2015 in “Hair transplant forum international” The review concluded that better studies are needed to prove if Low-Level Laser Therapy devices for hair growth really work.
November 2025 in “Journal of Investigative Dermatology”
8 citations
,
January 2017 in “Stem Cells International” This study found that overexpression of sFRP4 in skin cells reduces Wnt signaling activation, leading to decreased melanocyte differentiation in regenerating hair follicles.
13 citations
,
November 1996 in “International Journal of Dermatology” This article reviews the role of liposomes in dermatology and does not report new clinical results.
April 2023 in “Journal of Investigative Dermatology” This research reexamined transcriptomic data to study stem and progenitor cell proliferation in psoriasis, finding that the number of committed progenitor cells increased eight-fold in psoriatic skin without altering stem cell numbers, potentially identifying new therapeutic targets.
February 2009 in “Journal of The American Academy of Dermatology” This study suggests that fractional infrared technology may effectively improve cervical skin laxity by enhancing dermal thickness without adverse effects in a small pilot group.
7 citations
,
March 2001 in “Journal of the European Academy of Dermatology and Venereology” This case report highlights the complexity of lupus erythematosus/lichen planus overlap syndrome, noting a high potential for progression to systemic lupus erythematosus.
70 citations
,
April 2017 in “Lasers in surgery and medicine” This study found that blue light at a wavelength of 453 nm promoted hair growth ex vivo, potentially through interacting with OPN3 receptors in human hair follicles.
32 citations
,
August 1982 in “Journal of the American Academy of Dermatology” This study reports two cases of follicular lichen planus, suggesting that GLPLS and LPP may be variants of this condition based on clinical and immunofluorescent findings.