Lupus Erythematosus: What's New?

The document discussed lupus erythematosus (LE) and its overlap with lichen planus (LP), particularly focusing on cases with scarring alopecia. It highlighted the rarity and complexity of LE/LP overlap syndrome, which could potentially transform into systemic lupus erythematosus (SLE). The study noted that conversion from cutaneous lupus erythematosus (CLE) to SLE was more frequent in overlap syndromes, with a conversion rate of over 15% in long-term observations. The presence of low-titre Ro antibodies in CLE patients suggested a relationship between CLE and systemic forms like SLE and subacute cutaneous lupus erythematosus (SCLE). The document emphasized the importance of monitoring patients with atypical LE presentations for early signs of systemic involvement, given the high conversion rate to SLE.