Lupus Erythematosus: What's New?

    March 2001 in “ Journal of the European Academy of Dermatology and Venereology ”
    S Jabłońska, M Błaszczyk
    TLDR Lupus can progress to a more serious form, so careful monitoring is crucial.
    The document discussed lupus erythematosus (LE) and its overlap with lichen planus (LP), particularly focusing on cases with scarring alopecia. It highlighted the rarity and complexity of LE/LP overlap syndrome, which could potentially transform into systemic lupus erythematosus (SLE). The study noted that conversion from cutaneous lupus erythematosus (CLE) to SLE was more frequent in overlap syndromes, with a conversion rate of over 15% in long-term observations. The presence of low-titre Ro antibodies in CLE patients suggested a relationship between CLE and systemic forms like SLE and subacute cutaneous lupus erythematosus (SCLE). The document emphasized the importance of monitoring patients with atypical LE presentations for early signs of systemic involvement, given the high conversion rate to SLE.
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      If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      community If You Have DUPA, PLEASE READ THIS: Everyone Should Be Scalp Biopsied

      by nkrata in Research  830 upvotes 1 year ago
      Scalp biopsies are crucial for diagnosing hair loss conditions like Diffuse Unpatterned Alopecia (DUPA) and retrograde hair loss, as treatments like finasteride and dutasteride may not be effective if other conditions are present. Combining PPAR-GAMMA agonists with retinoids could improve treatments for conditions like Lichen Planopilaris.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  9 upvotes 5 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community 2 years of fin, 1.5 years of minoxidil, calling it quits. Thank you.

      in Shaved/buzzed  567 upvotes 2 years ago
      This user has been struggling with hair loss for the past two years and attempted to treat it using finasteride and minoxidil. Despite their efforts, they have not seen any improvement in their condition, so they have decided to shave or buzz their head instead. Others gave advice on other treatments that could be tried if desired.

      community Not everyone should immediately go on Fin if they are starting to bald

      in Finasteride/Dutasteride  21 upvotes 2 years ago
      The conversation suggests that people should consult a dermatologist to understand their type of hair loss before starting treatments like finasteride or dutasteride, especially if they have autoimmune issues or low DHT. Some participants believe in starting treatment like finasteride immediately if hair loss is due to DHT, while others recommend ruling out other causes and considering minoxidil first, especially for younger individuals.

      community Finasteride not working isnt it MPB?

      in Finasteride/Dutasteride  5 upvotes 1 year ago
      A user is concerned that finasteride isn't working for their hair loss, questioning if it's due to male pattern baldness or low iron levels. They are advised to take finasteride daily and get blood work done.

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