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Finasteride affects UGT1A4 enzyme, but not enough to cause issues when combined with other drugs.

Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.

The reconstructed skin model from hair follicles functions like human skin in processing chemicals and can be used to test ingredient safety.

New information shows Valproate may protect the brain and reduce breathing failure risk but can cause liver damage and other side effects, with genetics affecting dosage needs.

The document concludes that various findings in rheumatology offer insights into disease severity, treatment responses, and potential risks in medication, with some limitations due to unspecified participant numbers.

Different species and human skin models vary in their skin enzyme activities, with pig skin and some models closely matching human skin, useful for safety assessments and understanding the skin's protective roles.

The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.

Finasteride breakdown products found in bile and urine, helps understand drug safety and effectiveness.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

The Rotterdam Study updated findings on elderly health, focusing on heart disease, genetics, lifestyle effects, and disease understanding.

The study found that in Latin America, ancestry varies by location, influences physical traits, and affects how people perceive their own heritage.

The Rotterdam Study found risk factors for elderly diseases, links between lifestyle and genetics with health conditions, and aimed to explore new areas like DNA methylation and sensory input effects on brain function.

The Rotterdam Study aims to understand disease causes in the elderly and has found new risk factors and genetic influences on various conditions.

Two main types of fibroblasts with unique functions and additional subtypes were identified in human skin.

PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.

Red ginseng may improve immunity, fatigue, memory, blood circulation, and menopausal symptoms, and is generally safe to consume.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Researchers found 15 new genetic links to skin traits in Japanese women.

Activating Nrf2 protects human hair follicles from oxidative stress and helps prevent hair growth inhibition.

The gene for slick hair in Senepol cattle is located on chromosome 20 and may involve the SRD5A2 gene.

The method effectively detects banned substances in urine for sports antidoping.

Human enzymes can detoxify harmful substances but might also increase their cancer risk.

Valproic Acid could potentially be used to treat immune-related conditions due to its ability to modify immune cell functions.

Some natural compounds may help overcome drug resistance in certain cancers, but more research is needed.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.

Activating NRF2 might help treat hair disorders by improving antioxidant defenses.

Glutathione helps Arabidopsis roots adapt to low phosphate by regulating a specific growth pathway.

Spanish experts provided guidelines for treating skin side effects in cancer patients on new therapies, stressing early action and teamwork.

Genes linked to fibrosis are more active in people with central centrifugal cicatricial alopecia.