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    GlossaryThiazolidinediones (TZDs)

    medications that increase insulin sensitivity to treat type 2 diabetes

    Thiazolidinediones, also known as TZDs or glitazones, are a class of medications primarily used to treat type 2 diabetes. They work by increasing the body's sensitivity to insulin, thereby helping to control blood sugar levels. These drugs activate a specific receptor called PPAR-gamma, which influences the regulation of glucose and lipid metabolism.

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