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Hair ages due to genetics and environmental factors, leading to graying and thinning, with treatments available for some conditions.

A cluster of sulfur-rich hair protein genes was found on chromosome 17.

No treatment fully prevents hair loss from chemotherapy yet.

The p75 neurotrophin receptor is important for hair follicle regression by controlling cell death.

Notch/CSL signaling controls hair follicle differentiation through Wnt5a and FoxN1.

The Wnt/β-catenin pathway helps tissue regeneration but can also cause fibrosis, and drugs that inhibit this pathway may aid in healing skin and heart tissues.

Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.

Newborn mouse skin cells can grow hair and this process can be recreated in adult cells to potentially help with hair loss.

Low-oxygen conditions and ECM degradation products increase the healing abilities of perivascular stem cells.

Wool follicles are complex, involving interactions between different cell types and structures.

Fetal skin heals without scarring due to unique cells and processes not present in adult skin healing.

Conditioned media from mesenchymal stem cell cultures could be a more effective alternative for regenerative therapies, but more research is needed.

BMP2 and BMP7 have opposite roles in feather formation.

Activating the Wnt/β-catenin pathway could lead to new hair loss treatments.

Green tea may help with health issues like cancer, heart disease, and weight loss due to its high catechin content.

Mutant mice help researchers understand hair growth and related genetic factors.

The article concludes that while we understand a lot about how melanocytes age and how this can prevent cancer, there are still unanswered questions about certain pathways and genes involved.

Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

EGF and KGF signalling prevent hair follicle formation and promote skin cell development in mice.

Follistatin helps hair growth and cycling, while activin prevents it.

Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.

Muscles and nerves that cause goosebumps also help control hair growth.

SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.

Some common medications can harm male fertility, but many effects can be reversed.

Women with PCOS often have skin problems like excessive hair, acne, hair loss, and dark patches, which can be treated with hormonal and non-hormonal therapies.

Beta-sitosterol has potential health benefits but needs more research to fully understand its effects and improve its use in treatments.

Aging mice have slower hair regeneration due to changes in signal balance, but the environment, not stem cell loss, controls this, suggesting treatments could focus on environmental factors.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Hair grays due to oxidative stress and fewer functioning melanocytes.