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The document concludes that mouse models are crucial for studying hair biology and that all mutant mice may have hair growth abnormalities that require detailed analysis to identify.

Reductive stress messes up collagen balance and alters cell signaling in human skin cells, which could help treat certain skin diseases.

The TGF-β family helps control how cells change and move, affecting skin, hair, and organ development.

NF-κB signaling is crucial in many diseases and can be targeted for new treatments.

Fibroblasts, cells usually linked to tissue repair, also help regenerate various organs and their ability decreases with age. Turning adult fibroblasts back to a younger state could be a new treatment approach.

L-PGDS has specific binding sites for its functions and could help in drug delivery system design.

Lymphatic vessels are essential for health and can be targeted to treat various diseases.

Cyanidin 3-O-arabinoside may help treat a common form of hair loss by protecting cells against aging and improving cell function.

The Wnt/β-catenin pathway is important for body functions and diseases, and targeting it may treat conditions like cancer, but with safety challenges.

Regulatory T cells help heal skin and grow hair, and their absence can lead to healing issues and hair loss.

MSCs and their exosomes may speed up skin wound healing but need more research for consistent use.

Ultraviolet rays damage hair, smoking may cause hair loss, and good nutrition is important for hair health, but genetics mainly decide hair thickness.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Colchicine can inhibit hair growth by affecting cell activity and protein expression in hair follicles.

Some hair protein genes evolved early and were adapted for use in hair follicles.

The androgen receptor is a promising target for breast cancer treatment, especially in triple-negative cases, but more research is needed for personalized therapies.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

The secretions of mesenchymal stem cells could be used for healing without using the cells themselves.

Sex hormones, especially estradiol, can change chicken feather shapes and colors.

Researchers found that most genes affecting drug responses are not fully covered by commercial SNP chips, suggesting the need for more comprehensive tools to optimize drug selection based on genetics.

Researchers found a genetic link for hereditary hair loss but need more analysis to identify the exact gene.

Olive oil compounds may help prevent cancer in animals, but human results are mixed.

Using protein degradation to fight cancer drug resistance shows promise but needs more precise targeting and fewer side effects.

CDP is crucial for lung and hair follicle cell development.

Copper and iron cause keratin damage in hair by converting methionine to homocysteine.

Different forms of FGF5 either promote or inhibit hair growth.

Saw palmetto extract may help treat brain tumors by blocking a specific growth signal and blood vessel formation.

Mast cells and CD8 T cells interact closely in skin diseases, affecting each other's behavior and contributing to conditions like psoriasis and eczema.

Skin aging is due to impaired stem cell mobilization or fewer responsive stem cells.

Using rodents for research shows that health problems in the womb can cause diseases later in life.