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RNA editing significantly affects hair growth and follicle cycling in the Tianzhu white yak.

Androgenetic alopecia involves immune cell disruptions, especially increased CD4+ T cells around hair follicles.

GLI1 might protect against the start of skin cancer and is not linked to cancer severity.

Eyelid cells share signaling components but differ in pathway activity.

The skin systems of jawed vertebrates evolved diverse appendages like hair and scales from a common structure over 420 million years ago.

JAK inhibitors may help treat Alopecia Areata but need careful monitoring due to side effects.

New drugs targeting the JAK-STAT pathway show promise for treating inflammatory skin diseases.

The conclusion is that androgenetic alopecia and senescent alopecia have unique gene changes, suggesting different causes and potential treatments for these hair loss types.

New chemotherapy drugs cause skin side effects, but treatments like minocycline and tetracycline can help reduce them.

Chromium supplements don't help with weight loss or improve hormone and metabolism issues in people with polycystic ovary syndrome.

Bexxar treatment led to a high response rate in patients with advanced-stage, treatment-resistant follicular lymphoma.

Upadacitinib significantly improved a man's severe scalp condition when other treatments failed.

Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.

Targeted cancer therapies often cause serious skin problems that need careful management.

The conclusion is that Treg-targeted therapies have potential, but more knowledge of Treg biology is needed for effective treatments, including for cancer.

Zinc deficiency in children can cause skin issues and can be serious if not diagnosed and treated properly.

Regenerative pharmacology, which combines drugs with regenerative medicine, shows promise for repairing damaged body parts and needs more interdisciplinary research.

Hair loss in balding individuals is linked to changes in specific hair growth-related genes.

Mutations in the PTPRQ gene cause significant balance issues in mice due to hair bundle defects in the inner ear.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

ALA-PDT is effective and safe for chronic X-ray dermatitis, providing complete or partial remission.

Sp6 promotes tooth development by reducing follistatin levels.

Quercitrin may help treat hair loss by promoting hair growth and improving cell health.

Ptprq has multiple forms that change during inner ear development.

The skin protects the body, regulates temperature, senses touch, and makes vitamin D.

The study suggests that hypothyroidism may cause alopecia areata.

Alopecia areata is an autoimmune condition causing hair loss, linked to genetic factors and immune system issues, with no cure yet.

Patients with RASopathies have a higher risk of autoimmune disorders and should be routinely screened.

The document concludes that understanding how the skin's immune system and inflammation work is complex and requires more research to improve treatments for skin diseases.

Insulin resistance is a key factor in polycystic ovary syndrome, but genetics may also contribute.