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Scientists found out the structure of a human enzyme linked to prostate cancer and hair loss, which could help in designing drugs.

A child with a rare type of rickets showed some improvement with high doses of vitamin D, but such conditions often respond poorly to treatment.

Intravenous and oral calcium effectively treated vitamin D dependent rickets type II, improving growth and bone health.

New compounds called benzoquinolinones may treat conditions linked to excess DHT.

At least 87% of Indian men experience hair loss, with type II being most common and severity increasing with age.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

The new saw palmetto extract effectively inhibits an enzyme linked to prostate enlargement and may be as good as standard treatments.

5α reductase type 2 enzyme mutation and oxidative stress may increase androgenetic alopecia risk in Egyptians.

A child with a rare vitamin D-resistant condition improved with treatment.

More severe hair loss worsens quality of life in men.

Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.

Only a few hair-specific keratins are linked to inherited hair disorders.

Finasteride improves hair loss in women with hyperandrogenism.

Hair loss in women is common, starts in late 20s, and affects 30% of women over 50.

Asiasari radix extract promotes hair growth and increases protein synthesis and cell proliferation.

Sophora flavescens extract may help hair grow by affecting growth factors and blocking a hair-related enzyme.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.

The document explains how to identify different hair problems using a microscope.

Early onset hair loss linked to genetics and androgen levels.

Steroids, particularly estrogens and 5α-reductase inhibitors, affect blood vessel-related hair growth processes in hair follicle cells.

Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.

5α-Reductase inhibitors can help treat hair loss, acne, and prostate issues by reducing DHT levels.

Minoxidil and finasteride can slow or halt hair loss, but may have side effects.

Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.

Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.