research Expression of mRNA for Androgen Receptor, 5α-Reductase, and 17β-Hydroxysteroid Dehydrogenase in Human Dermal Papilla Cells
Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.
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research Relationship of the Metabolic Syndrome and Obesity to Polycystic Ovary Syndrome: A Controlled, Population-Based Study
Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
research Skin Keratins
Keratins are important for skin cell health and their problems can cause diseases.
research Office Diagnosis of Hair Shaft Defects
The document explains how to identify different hair problems using a microscope.
research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle
Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
research Does a Male Polycystic Ovarian Syndrome Equivalent Exist?
Early onset baldness in men may indicate a condition similar to PCOS, linked to heart disease, diabetes, and prostate issues.
research Medical Management of Male Pattern Hair Loss
Minoxidil and finasteride can slow or halt hair loss, but may have side effects.
research Sequence and Expression of Human Hair Keratin Genes
Human hair keratin genes are similar to mouse genes and are specifically expressed in hair follicles.
research Evolution of Trichocyte Keratins
Hair keratins evolved from ancient proteins, diversifying through gene changes, crucial for forming claws and later hair in mammals.
![Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions](/images/research/2aedba8c-b0ac-4fa3-9ac7-9f375a016bba/small/15581.jpg)
research Synthesis and 5α-Reductase Inhibitory Activity of 8-Substituted Benzo[ƒ]Quinolinones Derived from Palladium Mediated Coupling Reactions
Some newly made compounds can block an enzyme linked to hair loss and prostate growth, with one in particular being very selective.
research Synthesis and In Vitro Evaluation of 4-Substituted N-(1,1-Dimethylethyl)-3-Oxo-4-Androstene-17β-Carboxamides as 5α-Reductase Inhibitors and Antiandrogens
The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.
research The Susceptibility of Disulfide Bonds to Modification in Keratin Fibers Undergoing Tensile Stress
Disulfide bonds in keratin fibers break more easily under stress, especially when wet, affecting fiber strength.
research Hair Growth Promoting Effect of 4HGF Encapsulated with PGA Nanoparticles by β-Catenin Activation and Related Cell Cycle Molecules
PGA-4HGF may help treat hair loss by activating hair growth pathways and extending the hair growth phase.
research Genome-Wide Identification, Characterization, and Expression Analysis of Keratin Genes (KRTs) Family in Yak (Bos Grunniens)
Scientists found 53 keratin genes in yaks that are important for hair growth and share similarities with those in other animals.
research Incidence of Female Androgenetic Alopecia (Female Pattern Alopecia)
Female pattern alopecia is common, starts in late 20s, and is not androgen dependent.
research Pathomechanism of Androgenetic Alopecia and New Treatment
Male hormones can cause hair loss, but treatments like Minoxidil and Finasteride can help, and targeting TGF-B1 could be a future solution.
research Androgens and Women's Health
Excessive androgen in women can cause acne, hair growth, baldness, and PCOS, often treatable with medication.
research Finasteride as a Potential Tool to Improve Mesenchymal Stem Cell Transplantation for Myocardial Infarction
Finasteride may improve stem cell therapy for heart attacks by increasing cell survival.
research Comment on: The Gabrin Sign
The document suggests that more research is needed to confirm if baldness can indicate a higher risk of severe COVID-19 in men.
research Finasteride
Finasteride is a medicine used to treat enlarged prostate and prostate cancer, and it works by changing how testosterone works in the body.
research Pathomechanism of Androgenetic Alopecia and New Treatment
Male pattern baldness is caused by certain cells in hair follicles and could potentially be treated by targeting a specific growth factor, TGF-β1.
research Potential Role of Cinnamon (Cinnamomum Verum) to Reduce the Risk of Polycystic Ovary Syndrome by Managing Obesity: A Review
Cinnamon may help manage obesity and improve conditions related to Polycystic Ovary Syndrome (PCOS).
research A New Era of 5α-Reductase Inhibitors for Androgenetic Alopecia
New drug dutasteride effectively treats hair loss, but use cautiously due to potential sexual side effects.
research Male Androgenetic Alopecia
Male pattern baldness is mainly caused by genetics and hormones, treatable with minoxidil and finasteride.
research Hair Growth as Anti-Aging
Anti-aging treatments like hair transplants, minoxidil, and finasteride effectively promote hair growth.
research A Case of Severe Hyperandrogenism, Acanthosis Nigricans, and Overt Diabetes: The Use of Non-Invasive Methods for Diagnosis, Pathogenesis, and Management
Non-invasive imaging helped diagnose a woman's severe hormone imbalance and diabetes, and medication successfully treated her condition.
research Terminalia Bellirica (Gaertn.) Roxb. Extracts Reshape the Perifollicular Microenvironment and Regulate the MAPK Pathway for Androgenetic Alopecia Treatment
Terminalia bellirica extracts effectively promote hair regrowth and treat androgenetic alopecia.
research Finasteride
Finasteride treats hair loss and prostate issues by lowering certain hormone levels.
research The Role of Exosomes in Follicle Regeneration of Androgenic Alopecia
Exosomes may help stimulate hair growth and improve hair loss conditions like androgenic alopecia.
research Finasteride Induces Epigenetic Alteration of TMPRSS2 Gene Expression: A Potential Role in Severe Acute Respiratory Syndrome Coronavirus 2 Inhibition
Finasteride may help reduce COVID-19 infection by altering a key gene.