Terminalia Bellirica (Gaertn.) Roxb. Extracts Reshape the Perifollicular Microenvironment and Regulate the MAPK Pathway for Androgenetic Alopecia Treatment

    September 2024 in “ Journal of Ethnopharmacology ”
    Hong Xiang, Yukui Zhang, Jiaming Li … Yao Liu
    Studysummary In this study, Terminalia bellirica extracts promoted hair regrowth in testosterone-induced AGA mice, possibly by inhibiting type II 5α-reductase activity and enhancing the MAPK signaling pathway.
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    Research cited in this study 7

    1. Co-Delivery of Minoxidil and Tocopherol Acetate Ethosomes to Reshape the Hair Follicle Microenvironment and Promote Hair Regeneration in Androgenetic Alopecia International Journal of Pharmaceutics · 2023
    2. The In Vivo and In Vitro Effects of Terminalia Bellirica Fruit Extract on Testosterone-Induced Hair Loss Journal of Microbiology and Biotechnology · 2023
    3. Conditioned Media-Integrated Microneedles for Hair Regeneration Through Perifollicular Angiogenesis Journal of Controlled Release · 2022
    4. Ceria Nanozyme-Integrated Microneedles Reshape the Perifollicular Microenvironment for Androgenetic Alopecia Treatment ACS Nano · 2021
    5. Microneedles Mediated Bioinspired Lipid Nanocarriers for Targeted Treatment of Alopecia Journal of Controlled Release · 2020
    6. Quercitrin Stimulates Hair Growth with Enhanced Expression of Growth Factors via Activation of MAPK/CREB Signaling Pathway Molecules · 2020
    7. Molecular Basis of Androgenetic Alopecia: From Androgen to Paracrine Mediators Through Dermal Papilla Journal of Dermatological Science · 2010