This study elucidated the multi-component and multi-target mechanisms by which TR and Am may provide therapeutic benefits for treating androgenetic alopecia.
282 citations
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April 2007 in “Journal of Agricultural and Food Chemistry”
This study found that apple polyphenol extract, particularly oligomeric procyanidins, inhibited pancreatic lipase activity and reduced triglyceride absorption in both mice and humans.
This study found that the overall incidence rate of alopecia among female activecomponent service members in the U.S. military from 2010 to 2022 was 804.4 per 100,000 person-years, with Non-Hispanic Black and Hispanic women experiencing the highest rates.
Topical application of Eriodictyon angustifolium extract can prevent and reverse age-related beard graying and darken gray hair by increasing melanin production. Sterubin, a component of the extract, also promotes hair pigmentation and protects cells from DNA damage.
The conversation discusses skepticism about "5 in 1" and "3 in 1" hair loss treatments, which combine Dutasteride or Finasteride with Minoxidil, being overpriced and potentially ineffective. Users suggest buying individual components separately for cost savings and question the effectiveness of low concentrations in these combined products.
The conversation discusses "Hair bloom" hair filler, which contains biotin, collagen, and various peptides, as a potential alternative to PRP or mesotherapy for hair loss. Opinions vary, with some suggesting it may be a cash grab or ineffective, while others believe it could complement topical minoxidil for early hair loss.
Redensyl is a plant-based treatment that may support hair regrowth by reactivating dormant follicles and improving hair density, especially in early-stage thinning. It is not a miracle cure and results vary; it is less proven than Minoxidil or Finasteride and may cause scalp irritation.
Saw palmetto's fatty acids, particularly lauric and linoleic acids, inhibit enzymes linked to hair loss, while sterols like beta-sitosterol are less effective due to poor absorption. The conversation questions which specific compounds in saw palmetto contribute to its anti-androgenic effects.
Can glycerin be used in combination with active ingredients like minoxidil or tretinoin?Glycerin is a common humectant that formulators treat as compatible with topical actives, but no published trial has tested it alongside minoxidil or tretinoin, so any benefit is comfort rather than a proven effect. Tretinoin is prescription-only and carries pregnancy warnings.