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The gene SDR5A1 is found in scalp hair of both hirsute and normal individuals, but it does not explain differences in hair growth.

Low testosterone does not prevent prostate cancer in men with type 1 diabetes.

Researchers developed a method to measure different forms of a drug that could help treat prostate issues and hair loss, and found how these forms behave in animals.

The enzyme 5α-reductase is important for proper blood vessel development during the fertility-related transformation of the uterus lining.

Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.

The new compounds moderately block a specific enzyme and strongly counteract a male hormone, suggesting potential for treating certain male-related health conditions.

A 9-year-old girl developed type 1 diabetes and alopecia after being treated for a rare kidney disease.

Sleep, testosterone levels, and a specific enzyme activity affect skin oil production in women.

Mice lacking a key DNA methylation enzyme in skin cells have a lower chance of activating stem cells necessary for hair growth, leading to progressive hair loss.

New compounds were made that effectively block a specific enzyme related to androgen conditions.

Key enzymes control androgen levels, affecting hormone activity and potential treatments.

New compounds were made that effectively block enzymes related to prostate issues and hair loss.

PNU 157706 is a more effective treatment than finasteride for conditions caused by DHT, like enlarged prostate and hair loss.

Blocking the enzyme 5α-reductase can shrink the prostate and help treat enlarged prostate issues.

Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.

New chemicals were made that can block an enzyme linked to hair loss, prostate growth, and acne.

Human sebaceous glands contain enzymes that affect androgen production and may influence sebum production and acne.

Blocking the enzyme that turns testosterone into DHT can safely and effectively treat enlarged prostate.

Prostate cancer was a major health issue in 2009, especially for Black men, and targeting the 5alpha-reductase enzyme could help in its prevention and treatment.

Targeting glucocorticoid action might help treat type-2 diabetes, but human trials are needed.

Researchers developed a model to predict how well certain compounds can block an enzyme related to hair loss and prostate issues, suggesting a 50 mg dose of finasteride might be effective based on lab and body data.

Spironolactone works well for acne and hirsutism, isotretinoin is very effective for acne and may have antiandrogenic effects, and 5 alpha-reductase inhibitors should be considered antiandrogens.

Allopregnanolone is needed for certain brain processing issues caused by D1 dopamine receptor activation.

5AR inhibitors like finasteride and dutasteride improve hair growth and slow hair loss in male pattern baldness.

5α-reductase inhibitors, like finasteride and dutasteride, effectively treat BPH, male baldness, and hirsutism, with potential for acne and prostate cancer prevention.

Androgens may influence bladder cancer progression by affecting cellular behavior.

Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.

Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.

The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.

Dapsone gel 5% is effective and safe for treating acne.