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A young Saudi girl with uncontrolled type 1 diabetes and hypothyroidism had two rare conditions, Mauriac syndrome and Van Wyk–Grumbach syndrome.

Changing the C-ring structure in certain compounds can make them better at blocking a specific human enzyme.

Honokiol might help reduce male skin aging by maintaining testosterone levels.

People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.

Beta-sitosterol and stigmasterol might help prevent hair loss by blocking a specific enzyme.

ILC1 cells contribute to hair loss in alopecia areata.

Gene therapy shows promise for treating skin disorders and cancer, but faces technical challenges.

HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.

The document concludes that recognizing and properly diagnosing lipodystrophy syndromes is crucial for effective management and treatment.

Enzymes are classified into six types and are essential for many biological processes, with only a few targeted by drugs.

Plant-based products can improve hair and skin health without harmful side effects.

ePUKs could be valuable for regenerative medicine due to their wound healing abilities.

Methylated flavonoids may effectively reduce depression and inflammation caused by finasteride.

Cannabinoids like CBD and THC may help treat non-cancer skin diseases, but more research is needed.

Actinic keratosis can lead to skin cancer, is more common in fair-skinned people, and can be reduced with sunscreen and treated effectively.

Cheonggukjang may help prevent and manage various diseases and improve overall health, but its odor and safety concerns need addressing.

The study concludes that mutations in the AEBP1 gene can cause a form of Ehlers-Danlos syndrome and should be considered in diagnosis.

The update highlights that non-classic congenital adrenal hyperplasia is common in women with excess male hormones, requires specific hormone tests for diagnosis, and has various treatment options depending on age and symptoms.

ZDHHC13 is important for normal liver function and metabolism, affecting mitochondrial activity.

Some growth factors, while important for normal body functions, can cause diseases when not regulated properly.

Combination therapy improves hair growth in advanced hair loss.

Skin reactions are a common reason for emergency visits due to drug allergies, with some severe cases needing intensive care.

Mimicking growth factors in a topical solution can prolong hair growth phase and reduce hair loss without side effects.

A woman with CHILD syndrome showed skin abnormalities, and the report suggests CHILD nevus and NEVIL might be the same condition, highlighting the need for diagnosis for genetic advice.

A woman's nail separation was likely caused by poor blood flow, and a treatment for similar conditions might help.

Surgery on a baby with a skin disorder improved eyelid position and eye health.

Hirsutism causes significant psychological distress in women.

Gray hair can potentially be reversed, leading to new treatments.

AKR1D1 controls glucocorticoid levels and receptor activity in liver cells.

Finasteride in male rats causes liver and metabolic issues in their offspring.