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Hormones, especially androgens, play a key role in causing acne, and treatments like hormone control pills and hormone-blocking medications can help.

We need to learn more about 5α-reductases and neuroactive steroids to safely make drugs targeting these enzymes.

Annurca apple extract improved hair growth in mice and could potentially prevent hair loss.

New treatments for enlarged prostate are being developed to be more effective and have fewer side effects.

Plant-based compounds might be effective, low-side-effect treatments for prostate cancer by blocking a specific enzyme.

5-alpha reductase inhibitors can cause sexual side effects like erectile dysfunction and reduced sexual desire, sometimes lasting after stopping the drug.

Both drugs lower DHT levels, with GI198745 being more effective.

New pregnane derivatives were more effective than finasteride at inhibiting a key enzyme for male pattern baldness.

Medications for enlarged prostate can cause sexual side effects like reduced libido, erectile dysfunction, and ejaculatory problems.

Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.

5α-reductase inhibitors can cause serious and possibly lasting sexual and psychological side effects.

Some patients taking finasteride or dutasteride may have ongoing sexual problems and depression even after stopping the medication.

Finasteride effectively reduces hair growth in women with idiopathic hirsutism, but requires careful contraception during treatment.

Plant extracts like Avicennia marina, Boehmeria nipononivea, and Camellia sinensis could potentially treat hair loss with fewer side effects than synthetic drugs.

5α-reductase is essential for male sexual development and its inhibitors have potential in treating various conditions related to hormone action.

A new method was created to test the effectiveness of Dihydrotestosterone (DHT) inhibitors, like finasteride and dutasteride, in human and fish cells. The results showed fish cells are more sensitive to these treatments, and dutasteride works better than finasteride in all tested cells.

Finasteride 5mg daily is the most effective for female pattern hair loss, with higher doses of treatments generally more effective.

5-alpha reductase inhibitors may help protect the brain and gut in Parkinson's disease.

5α-reductase inhibitors can interfere with doping tests by masking banned substances.

Too much AKR1C3 enzyme causes resistance to finasteride by increasing testosterone.

PNU157706 reduced rat sperm movement and fertility without affecting offspring health.

Finasteride doesn't affect erections much, but may decrease libido in men.

Eclipta alba extract could be a promising natural treatment for hair loss.

The new particle system could be a promising treatment for diseases related to the 5-α reductase enzyme.

Taking 5 alpha reductase inhibitor medication slightly increases the risk of depression, especially as you get older.

Treatments for hair loss vary, but cell-based options may be the future.

Hormonal treatments can help with acne, especially in women, by lowering androgen levels or blocking their effects.

Enzymes called 5α-reductases have many body functions and need more research to safely use inhibitors.

COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.

Finasteride affects the male rat brain by reducing certain protein activation, but these effects may reverse after stopping the drug.