research An Adolescent Girl with Coexisting Ovarian Mature Cystic Teratoma and HAIR-AN Syndrome, an Extreme Subtype of Polycystic Ovarian Syndrome
A teenage girl had both a rare ovarian tumor and a severe form of polycystic ovarian syndrome.
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330-360 / 1000+ results research Cyclin D3 Deficiency Inhibits Skin Tumor Development But Does Not Affect Normal Keratinocyte Proliferation
Lacking cyclin D3 reduces skin cancer growth without affecting normal skin cell growth.
research Advancing Skin Model Development: A Focus on a Self-Assembled, Induced Pluripotent Stem Cell-Derived, Xeno-Free Approach
A new ethical skin model using stem cells offers a reliable alternative for dermatological research.
research Modeling of Ionizing Radiation Induced Hair Follicle Regenerative Dynamics
Hair follicles can regenerate after radiation damage but not during a specific growth phase.
research Controlled Delivery of T-box21 Small Interfering RNA Ameliorates Autoimmune Alopecia in a C3H/HeJ Mouse Model
Controlled delivery of specific RNA and IL-4 restored hair growth in mice with autoimmune alopecia.
research Prevention and Treatment of Alopecia Areata with Quercetin in the C3H/HeJ Mouse Model
Quercetin effectively treated and prevented hair loss in mice.
research The Hair Follicle: Functions, Self-Renewal, and Alopecic Disorders
Dogs could be good models for studying human hair growth and hair loss.
research Alopecia Areata: Pathogenesis, Genetic Factors, and Treatments Using Mouse Models
The document concludes that ongoing research using animal models is crucial for better understanding and treating Alopecia Areata.
research Hedgehog Pathway Inhibitors Against Tumor Microenvironment
Hedgehog pathway inhibitors can treat certain aggressive cancers but face limitations like resistance and side effects.
research Establishment and Characterization of a Radiation-Induced Dermatitis Rat Model
Researchers created a rat model to study skin damage caused by radiation, which could help develop new treatments.
research Nailing It
The document concludes that a new training model could improve dermatology residents' skills in nail procedures and lead to more nail cases being treated by dermatologists.
research Research Techniques Made Simple: Zebrafish Models for Human Dermatologic Disease
Zebrafish are useful for studying and developing treatments for human skin diseases.
research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research MTurq2-Col4a1 Mouse Model Allows for Live Visualization of Mammalian Basement Membrane Development
The mTurq2-Col4a1 mouse model shows how the basement membrane develops in live mammals.
research Immunoregulatory Effects of Myeloid-Derived Suppressor Cell Exosomes in Mouse Model of Autoimmune Alopecia Areata
MDSC-Exo can treat autoimmune alopecia areata and promote hair regrowth in mice.
research Understanding Melanocyte Stem Cells for Disease Modeling and Regenerative Medicine Applications
Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.
research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model
Superoxide dismutase (SOD) can prevent hair graying in mice.
research Meis1 Regulates Epidermal Stem Cells and Is Required for Skin Tumorigenesis
Meis1 is crucial for skin health and tumor development.
research Anticancer Effects of Metformin on Neuroendocrine Tumor Cells In Vitro
Metformin may help treat neuroendocrine tumors.
research Hair Follicle Regeneration Suppresses Ras-Driven Oncogenic Growth
Hair follicle regeneration may slow tumor growth.
research Protective Effect of Superoxide Dismutase Against Hair Graying in a Mouse Model
Superoxide dismutase (SOD) can prevent hair graying in mice.
research Wound Healing Impairment in Type 2 Diabetes Model of Leptin-Deficient Mice: A Mechanistic Systematic Review
Leptin-deficient mice, used as a model for Type 2 Diabetes, have delayed wound healing due to impaired contraction and other dysfunctional cellular responses.
research Side Gland of Suncus Murinus as a New Model of Sebaceous Gland: 5α-Reductase, Androgen Receptor, and Nuclear Androgen Content in Male and Female Animals
The side gland of Suncus murinus is a good model for studying human sebaceous glands.
research Dermal Lymphatic Dilation in a Mouse Model of Alopecia Areata
Mice with alopecia areata had wider lymphatic vessels in their skin.
research Ovarian and Adrenal Androgens and Their Link to High Human Chorionic Gonadotropin Levels: A Prospective Controlled Study
Women with a certain type of tumor had higher levels of pregnancy hormone and male hormones, which decreased after treatment.
research Melanocytes in Regenerative Medicine Applications and Disease Modeling
Melanocytes are important for normal body functions and have potential uses in regenerative medicine and disease treatment.
research Assessment of Multidimensional Health Care Parameters for Developing a Virtual Human Generative Model: A Cross-Sectional Study in Japan
The study aims to create a model to predict health attributes using diverse health data from Japanese adults.
research Deletion of the MAD2L1 Spindle Assembly Checkpoint Gene Is Tolerated in Mouse Models of Acute T-Cell Lymphoma and Hepatocellular Carcinoma
Deleting the MAD2L1 gene is tolerated in certain mouse cancer models.
research Editors' Picks
Collagen VII helps skin heal and stay strong, sirolimus may lower skin cancer risk in kidney transplant patients, high-molecular-mass hyaluronan helps naked mole rats resist cancer, dermal γδ T cells aid in hair growth in rodents, and overexpression of IL-33 in mouse skin causes itchiness, offering a model for studying allergic inflammation treatments.
research Effect of the Dual 5α-Reductase Inhibitor Dutasteride on Markers of Tumor Regression in Prostate Cancer
Dutasteride may help treat prostate cancer by causing cancer cells to shrink and die.