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The 2015 Hair Research Congress concluded that stem cells, maraviroc, and simvastatin could potentially treat Alopecia Areata, topical minoxidil, finasteride, and steroids could treat Frontal Fibrosing Alopecia, and PTGDR2 antagonists could also treat alopecia. They also found that low-level light therapy could help with hair loss, a robotic device could assist in hair extraction, and nutrition could aid hair growth. They suggested that Alopecia Areata is an inflammatory disorder, not a single disease, indicating a need for personalized treatments.

p14ARF and p16Ink4a cause hair follicle stem cell aging and dysfunction.

Skin stem cells interacting with their environment is crucial for maintaining and regenerating skin and hair, and understanding this can help develop new treatments for skin and hair disorders.

Targeted anticancer therapies can cause severe side effects similar to traditional chemotherapy, but with different types.

YAP and TAZ are crucial for skin cell growth and repair.

Essential oils from Curcuma species, like turmeric, have compounds that can fight inflammation, cancer, and bacteria, and can also stimulate hair regrowth in bald males.

A new mutation in the Connexin 26 gene was found in a patient with KID syndrome, expanding the known disorders linked to this gene.

miR-31 regulates hair growth by controlling gene expression in hair follicles.

Deregulation of stem cell function is central to the development of some cancers.

Licorice has many health benefits but should be used carefully due to possible side effects.

Targeting the Smoothened receptor shows promise for treating certain cancers.

Vemurafenib causes skin side effects similar to RASopathies, requiring regular skin checks and UVA protection.

The Hedgehog signaling pathway is important for skin and hair growth and can lead to cancer if it doesn't work right.

Probiotics show promise for health benefits but need more research to understand how they work.

Dissolving microneedles show promise for delivering medication through the skin but face challenges like manufacturing complexity and regulatory hurdles.

GLP-1 receptor agonists, like Dulaglutide, Liraglutide, and Semaglutide, have potential benefits beyond the pancreas, including neuroprotection, pain suppression, cardiovascular protection, obesity management, and cancer treatment, but there are concerns about pancreatitis and pancreatic cancer risks.

The project created a standardized system for classifying skin lesions in lab rats and mice.

Heavy ion radiation has a more severe and long-lasting effect on mouse intestinal metabolites than gamma radiation.

Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.

Folliculin deficiency causes problems with cell division and positioning due to disrupted RhoA signaling and interaction with p0071.

Combining irinotecan and cetuximab is effective for some metastatic colorectal cancer patients but often causes manageable skin issues.

Proxalutamide helps COVID-19 patients get rid of the virus faster and recover quicker.

Dutasteride treatment in men with mild to moderate COVID-19 reduced viral shedding, inflammation, and recovery time without serious side effects.

The document concluded that more research is needed to find the best treatment for Frontal fibrosing alopecia.

Gene therapy shows promise for healing chronic wounds but needs more research to overcome challenges.

Melanocyte stem cells are crucial for skin pigmentation and have potential in disease modeling and regenerative medicine.

Testosterone may influence COVID-19 severity and outcomes.

The Msi2 protein helps keep hair follicle stem cells inactive, controlling hair growth and regeneration.

Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.

Natural small molecules can help treat diseases by activating or inhibiting the Wnt pathway.