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Dermatopathology has made significant progress but many skin diseases remain incurable, requiring ongoing research.

Most skin tumors in the study were benign, with squamous cell carcinoma being the most common malignant type.

Prostaglandin E2 affects human platelet activity in complex ways that could lead to personalized heart disease treatments.

New treatments for prostate cancer and BPH show promise, including novel compounds that target hormone synthesis and response.

Topical glucocorticoids thin the skin and change collagen structure.

A special gel with medicine helps prevent melanoma from coming back after surgery.

The document concludes that understanding the sebaceous gland's development and function is key to addressing related skin diseases and aging effects.

Keratin mutations cause skin diseases and could lead to new treatments.

Overexpression of HDGF in melanocytes does not cause cancer.

Nano-Pulse Stimulation™ Therapy is more effective and less damaging than cryoablation for treating melanoma tumors in mice.

Injectable hydrogels are becoming increasingly useful in medicine for drug delivery and tissue repair.

Removing part of the vitamin D receptor stops vitamin D from working properly.

Vitamin D receptor may help protect against UV-induced skin cancer.

Low androgen levels might delay prostate cancer but could lead to more aggressive, therapy-resistant cancers.

Eph/ephrin signaling is important for skin cell behavior and could be targeted to treat skin diseases.

NF-κB is crucial for different stages and types of hair growth in mice.

Intu gene is crucial for hair follicle formation by helping keratinocytes differentiate through primary cilia.

Lipocalin-Type Prostaglandin D2 Synthase (L-PGDS) is a protein that plays many roles in the body, including sleep regulation, pain management, food intake, and protection against harmful substances. It also affects fat metabolism, glucose intolerance, cell maturation, and is involved in various diseases like diabetes, cancer, and arthritis. It can influence sex organ development and embryonic cell differentiation, and its levels can be used as a diagnostic marker for certain conditions.

Nitric Oxide has potential in medicine, especially for infections and heart treatments, but its short life and delivery challenges limit its use.

Extracellular vesicles show promise for wound healing, but more research is needed to improve their stability and production.

Organic and biogenic nanocarriers can improve drug delivery but face challenges like consistency and safety.

Research from 2011 to 2020 shows androgen receptors could be key for prognosis and treatment in certain breast cancers.

B2m-free HLA variants may be a new class of HLA important in immune responses and diseases.

The cornified envelope is crucial for skin's barrier function and involves key proteins and genetic factors.

Keloid skin disorder involves abnormal fibroblast activation and immune response, linked to a group of genes including FGF11.

Some canine hair follicle tumors contain amyloid deposits, with a protein called CK5 involved in their formation.

Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.

Skin cancer in sun-exposed areas is more likely to come back.

Scientists have improved 3D models of human skin for research and medical uses, but still face challenges in perfectly replicating real skin.

The May issue discussed publishing agreements and four studies on cholesterol in hair, cancer cell changes, hormones in the uterus, and skin protein effects.