July 2023 in “Journal of Biomedical Science” Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
16 citations,
July 2012 in “Current pharmaceutical biotechnology” New treatments for skin conditions related to the sebaceous gland are being developed based on current research.
8 citations,
May 2019 in “Journal of dermatological treatment” Vismodegib is effective for basal cell carcinoma but has severe side effects.
17 citations,
December 2019 in “Stem Cell Research & Therapy” Grouping certain skin cells together activates a growth pathway that helps create new hair follicles.
23 citations,
March 2001 in “Clinics in dermatology” Alopecia areata involves immune response and gene changes affecting hair loss.
5 citations,
July 2014 in “Acta Crystallographica Section D-biological Crystallography” Mutations in the enzyme don't significantly change how it binds to its specific substances.
75 citations,
September 2007 in “Journal of Heredity” FGF5 gene mutations cause long hair in domestic cats.
109 citations,
October 2007 in “Journal of pineal research” Melatonin helps regulate hair growth and protects the hair follicle from stress.
84 citations,
July 2003 in “European journal of biochemistry” Mouse skin can produce and process serotonin, with variations depending on hair cycle, body location, and mouse strain.
57 citations,
March 2013 in “Journal of Dermatological Science” Improving the environment and cell interactions is key for creating human hair in the lab.
9 citations,
January 2015 in “Current problems in dermatology” Scientists have found specific genes linked to different hair loss conditions, which could lead to new treatments.
63 citations,
September 2009 in “Regenerative Medicine” Scientists found a way to grow human hair cells in a lab that can create new hair when transplanted.
35 citations,
August 2010 in “The American journal of pathology” Researchers created a new mouse model for studying Citrullinemia Type I and similar conditions, showing symptoms and treatment responses like those in humans.
13 citations,
May 2005 in “Seminars in Plastic Surgery” Follicular Cell Implantation might become a new treatment for hair loss and could lead to advances in organ regeneration.
5 citations,
February 2011 in “Expert Opinion on Drug Discovery” We need better treatments for hair loss, and while test-tube methods are helpful, they can't fully replace animal tests for evaluating new hair growth treatments.
402 citations,
August 2011 in “Cancer research” Prostate cancer cells can make their own androgens to activate the androgen receptor, and treatments like abiraterone may increase this ability, suggesting new therapies should target the entire steroid-making pathway.
252 citations,
January 2008 in “Trends in Endocrinology and Metabolism” Melatonin in the skin helps protect against damage from stress and UV rays, and could be used to treat certain skin conditions.
122 citations,
July 2005 in “The FASEB journal” Hair follicles produce and respond to melatonin, affecting hair growth and sensitivity to estrogen.
103 citations,
October 2003 in “Birth Defects Research” Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
45 citations,
February 2018 in “Journal of basic and clinical physiology and pharmacology/Journal of basic & clinical physiology & pharmacology” *Acorus calamus* has many medicinal benefits but needs more safety research.
41 citations,
December 2015 in “Journal of the European Academy of Dermatology and Venereology” The conclusion is that a new biopsy technique and humidity chamber help study skin mites better and suggest mite overpopulation may cause skin diseases.
36 citations,
December 2002 in “Experimental dermatology” Barley extract, specifically procyanidin B-3, can promote hair growth and counteract growth inhibition.
15 citations,
August 2022 in “Journal of endocrinological investigation” Vitamin D and calcium are important for quick and effective skin wound healing.
2 citations,
December 2016 in “Experimental cell research” The research found a way to identify and study skin cells with stem cell traits, revealing they behave differently in culture and questioning current stemness assessment methods.
August 2023 in “International journal of medical science and clinical research studies” PRP therapy helps heal pediatric surgical wounds faster and with fewer scars but needs more research for safety and cost.
35 citations,
August 2016 in “Experimental Dermatology” Fullerene C60 shows promise as a new treatment for various skin conditions.
November 2021 in “Current Otorhinolaryngology Reports” New treatments for hair loss could involve using stem cells and a process called the Wnt/beta-catenin pathway to stimulate hair growth.
March 2024 in “Frontiers in endocrinology” A new MTX2 gene mutation caused a severe genetic disorder in a young Chinese girl.
23 citations,
December 2017 in “Scientific Reports” ARL15 is important for fat cell development and the release of the hormone adiponectin.
May 2015 in “Journal of Investigative Dermatology” Melanoma risk tools need improvement, a gene mutation causes a hair disorder that might be treated by managing cell stress, a potential therapy for a skin-ear disorder involves blocking cell channels, skin wrinkling may indicate lung aging regardless of smoking, and oxidative stress might contribute to common baldness.