25 citations
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July 1994 in “Journal of Cell Science” This study found that polyomavirus large T-immortalized rat dermal papilla cells retain hair-inductive ability and provide a viable model for studying hair growth and cytokine expression.
46 citations
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April 2009 in “Journal of Dermatological Case Reports” This study established standard trichoscopy norms for adult white females, providing benchmarks for hair thickness, percentage of thin hairs, and pilosebaceous units with single hair across different scalp areas.
29 citations
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August 1999 in “Journal of Investigative Dermatology” New mutations in hair keratin genes cause the rare hair disorder monilethrix.
May 2008 in “10th European Congress of Endocrinology” This study discovered that TTR is expressed in the human placenta as early as 6 weeks gestation, with increased levels in the first trimester potentially facilitating thyroid hormone delivery to the fetus.
January 2017 in “Enlighten: Publications (The University of Glasgow)” This study found that in mice with deregulated β-catenin and PTEN signaling, increased follicular hyperplasia and sebaceous gland changes occur, but typical papillomas do not develop, potentially due to p21 response and reduced stem cell markers.
2 citations
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May 2022 in “Clinical, Cosmetic and Investigational Dermatology” This study reports that quantitative trichoscopy, while noninvasive and convenient, provides less accurate hair density data compared to invasive histopathologic examination, which was demonstrated in a sample of adult Chinese individuals without alopecia.
January 2021 in “International journal of dermatology, venereology and leprosy sciences” This study identified specific trichoscopic features in patients with androgenetic alopecia and telogen effluvium, highlighting differences in hair shaft diameter variation between fronto-temporal and occipital areas.
9 citations
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January 2014 in “World journal of gastroenterology” This report describes a case where a gluten-free diet may have resolved trichotillomania in a young patient, suggesting a relationship between celiac disease and certain behavioral disorders.
91 citations
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December 2000 in “The journal of cell biology/The Journal of cell biology” This study reports that expressed mouse type Ia and type IIa trichocyte keratins were successfully assembled into intermediate filaments in vitro, while also suggesting that disulfide bond cross linking enhances their stability.
November 2023 in “International Journal of Trichology” In this study, researchers observed that trichoscopy could reliably identify features such as anisotrichosis and signs associated with inflammation and fibrosis in female pattern hair loss, which may aid in assessing disease severity and guiding treatment decisions.
28 citations
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October 2010 in “Targeted Oncology” This case report presents an instance of tufted hair folliculitis in a woman treated with trastuzumab, highlighting a previously unreported skin side effect of this selective HER2 inhibitor.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” In a laboratory setting, this study found that Biotrinine® dry extract activated hair follicle growth pathways and increased certain growth factor secretions in human dermal papilla cells, suggesting potential benefits for treating chronic hair loss.
26 citations
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January 1993 in “Dermatology” This report describes a new case of isolated trichothiodystrophy with characteristic brittle hair and suggests a simplified classification scheme for understanding sulfur-deficient hair disorders.
March 2022 in “International Journal of Trichology” This case study reported that prolonged use of the cancer drug Erlotinib in a postmenopausal woman was associated with trichomegaly and hypertrichosis, highlighting the importance of considering medication history in such cases.
2 citations
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January 2018 in “International Journal of Trichology” This case report describes trichothiodystrophy in two sisters with only hair fragility, illustrating the condition's variable presentation and the importance of regular monitoring for potential associated impairments.
January 2020 in “Medpulse International Journal of General Medicine” This study observed that trichoscopic patterns, such as yellow dots and honey comb patterns, correlate with the severity of androgenetic alopecia in Indian patients, highlighting trichoscopy's diagnostic and prognostic value.
August 2017 in “Journal of evolution of medical and dental sciences” In this study, researchers evaluated trichoscopy in diagnosing non-scarring alopecia and found diagnostic value in observing diverse hair diameters in androgenetic alopecia, black dots and broken hairs in alopecia areata, and empty follicles in telogen effluvium, supporting trichoscopy's utility in differentiating alopecia types.
December 2025 in “TURKDERM” This article discusses Trikostazis spinuloza (TS), a dermatological condition often misdiagnosed, and reviews its demographic, clinical, and dermoscopic features, but reports no new clinical results.
July 2026 in “International Journal of Health Science” In this narrative review, researchers found that biomimetic peptides, which mimic natural biological functions, show potential in improving hair density and thickness in people with alopecia, although more robust clinical studies are needed to confirm their efficacy for clinical use.
January 2018 in “Our Dermatology Online” This case report describes a carpenter who presented with contact dermatitis and trichopathy with whitish nodules in the axillary hair.
In this study, researchers found that follicular and epidermal transglutaminases are biochemically and immunologically distinct, suggesting the possibility of selectively modifying hair or epidermal proteins.
139 citations
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September 2001 in “The journal of investigative dermatology/Journal of investigative dermatology” This case report describes a patient with mutations in both alleles of the vitamin D receptor who exhibited hair loss clinically indistinguishable from generalized atrichia with papules, suggesting a potential genetic pathway shared with the hairless gene.
37 citations
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January 2017 in “International Journal of Dermatology” This study found that trichoscopic features like exclamation mark hairs and angulated hairs were more indicative of alopecia areata in an Asian population, while features like broken hairs of different lengths and flame hairs were more common in trichotillomania.
59 citations
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September 2007 in “Biochemical and Biophysical Research Communications” This study found that a gain-of-function mutation in the TRPV3 channel leads to altered hair development in DS-Nh mice by affecting the anagen and telogen phases, highlighting TRPV3's role in hair growth regulation.
16 citations
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October 2022 in “Biomimetics” This study found that Trichosanthes kirilowii extract significantly enhances keratinocyte proliferation and wound healing in vitro and in vivo, suggesting its potential as a wound-healing component.
December 2023 in “Journal of ethnopharmacology” This study found that tribuloside, a flavonoid from Tribulus terrestris L., enhances melanin production in human melanocytes, zebrafish, and human skin samples without causing toxicity, potentially through inhibiting PDE to increase cAMP levels and promote the melanin biosynthesis pathway.
11 citations
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March 2021 in “The journal of investigative dermatology/Journal of investigative dermatology” This study found that hair loss in an Olmsted syndrome mouse model with a Trpv3 mutation was linked to premature keratinocyte maturation, affecting hair follicle structure and function.
In this case report, a 65-year-old man's neck lesion was initially misdiagnosed as benign but later identified as trichilemmal carcinoma, with the authors recommending Mohs Micrographic Surgery as the preferred treatment option for this rare condition.
8 citations
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September 2021 in “Skin appendage disorders” This review discusses trichotillomania, including its diagnosis and management, and emphasizes the importance of a psychiatry-dermatology liaison alongside behavioral therapy and pharmacological options.
2 citations
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May 2024 in “International Journal of Dermatology”