Search

everythingexperts & clinicslearnfaqsresearchcommunity

for

Search:↓

This phase I study reported that ETC-159, targeting Wnt signalling, showed tolerable safety profiles at doses that inhibit its pathway, though bone turnover markers increased, warranting early and regular monitoring. No tumor responses were observed, but two patients achieved stable disease for several cycles.

In this study, two cases of idiopathic hair casts in young girls responded well to 0.025% tretinoin lotion, with analyses suggesting an infrainfundibular origin for the lesions.

This study found that using a trapezoid strip in hair transplantation for androgenetic alopecia minimizes follicular unit transection and yields significantly more grafts compared to an elliptical strip.

This article describes a new T-Fast multi-implanter that potentially reduces operating costs and surgical time by implanting two follicular unit excision grafts simultaneously, which may encourage clinics to adopt this technique.

This study found that deleting Stim1 and Stim2 in mature T regulatory cells disrupts Ca 2+ signaling, preventing their differentiation and leading to severe autoimmune disorders in mice.

In this study, Ritlecitinib was reported as a newly approved treatment for alopecia areata that can be used in patients aged 12 and older; after 24 weeks, it resulted in 80% or more scalp hair coverage in treated patients compared to a placebo.

This review discusses managing common and notable adverse events associated with the antibody-drug conjugate trastuzumab deruxtecan in patients with HER2-positive unresectable/metastatic breast cancer and reports no new clinical results.

This case report suggests that Trichostasis spinulosa should be considered in diagnosing treatment-resistant open comedone-like lesions and that skin surface biopsy might be an effective diagnostic method.

In this report, an 18-year-old female with trichotillomania was successfully treated using the glutamate modulator n-acetylcysteine.

CTP-543 effectively promotes hair regrowth in adults with moderate to severe alopecia areata.

This article reviews trichoscopic techniques for diagnosing common hair loss conditions and presents a revised algorithm for identifying specific features of cicatricial and noncicatricial alopecia, but reports no new clinical results.

This case report describes a rare instance of trichogerminoma with unusually numerous mitotic figures and a higher Ki67 proliferative rate, distinguishing it from previously documented cases.

In this study, Trichoscan®, reflectance confocal microscopy, and optical coherence tomography were found to be reliable noninvasive tools for measuring hair growth and follicle analysis after hair removal.

This study found that a specific T-cell receptor motif associated with lipid-antigen stimulation may play a role in the pathogenesis of folliculotropic mycosis fungoides.

This review discusses the characteristics, prevalence, and treatment challenges of trichotillomania and provides no new clinical findings.

This study reported improvements in trichotillomania symptoms among patients who engaged with a psychodermatology service, despite a high rate of missed appointments.

In this study, researchers identified elongated corkscrew hairs as a new trichoscopic pattern in immunosuppressed adults with chronic endothrix tinea capitis, which may help in earlier diagnosis and targeted mycological investigation.

This study highlights the significant pharmacological potential of Tridax procumbens, a plant with various therapeutic properties such as liver protection, immune modulation, and wound healing, though it notes that more research is needed to identify its active compounds and mechanisms for drug discovery.

This study found that immunohistochemistry can effectively distinguish between tricholemmoma and basal cell carcinoma, with BerEP4 and CD34 serving as key differentiators.

This study evaluated Tridax procumbens extracts for their in-vitro alpha amylase inhibitory activity compared to standard antidiabetic agents, suggesting potential benefits for diabetes management.

TICE salvage chemotherapy is effective for treating germ-cell tumors with poor prognosis.

This study found that trichoscopy is a valuable tool for diagnosing various hair disorders by identifying specific trichoscopic patterns, such as hair diameter diversity in androgenetic alopecia and exclamatory marks in alopecia areata.

Temporal triangular alopecia is a lifelong condition with hairless patches on the side of the head that may be present from birth.

In this study, hair shafts from trichothiodystrophy patients with ERCC2 mutations revealed abnormal cuticle structures and protein imbalances compared to normal hair shafts.

This study proposes that combining trazodone and clomiphene citrate could potentially restore libido synaptic circuits and treat post-finasteride syndrome, which involves persistent sexual dysfunction after discontinuing finasteride treatment.

Tiger tail banding and hair abnormalities are reliable indicators for diagnosing trichothiodystrophy.

This review outlines the phytochemical composition and pharmacological potential of Tridax procumbens, a plant traditionally used in various regions for its purported medical benefits, including antioxidant, antimicrobial, and anti-inflammatory effects, among others.

This study concluded that TrichoScan is error-prone in its current form and overestimates certain hair growth parameters, with results not aligning with clinical severity of alopecia.

This article reviews optimal patient selection and donor site quality for successful hair transplant procedures, but reports no new clinical findings.

This review discusses the clinical features of trichotillomania and the challenges in its diagnosis and treatment, reporting no new clinical findings while highlighting the need for specialized therapy and better therapeutic options.