Trichostasis Spinulosa Confirmed by Standard Skin Surface Biopsy

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    Studysummary This case report suggests that Trichostasis spinulosa should be considered in diagnosing treatment-resistant open comedone-like lesions and that skin surface biopsy might be an effective diagnostic method.
    Our plain-language summary. Not medical advice or a treatment recommendation. Consult a qualified healthcare professional before changing treatment. Full disclaimer
    Trichostasis spinulosa (TS) was confirmed in a 25-year-old female patient using a Standard Skin Surface Biopsy (SSSB), a non-invasive diagnostic method. The patient presented with black spots on her cheeks and nose, which had been misdiagnosed as acne for 12 years. SSSB revealed multiple vellus hair bundles in funnel-shaped structures, confirming TS. Treatment with 0.025% tretinoin and 4% erythromycin gel significantly reduced the lesions, but they recurred after treatment was stopped due to pregnancy. The study suggested that TS should be considered in the differential diagnosis of treatment-resistant comedone-like lesions and that SSSB is an effective and inexpensive diagnostic method.
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