Trichostasis Spinulosa Confirmed by Standard Skin Surface Biopsy

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    TLDR Trichostasis spinulosa can be diagnosed with a simple skin biopsy and treated with specific gels, but lesions may return after stopping treatment.
    Trichostasis spinulosa (TS) was confirmed in a 25-year-old female patient using a Standard Skin Surface Biopsy (SSSB), a non-invasive diagnostic method. The patient presented with black spots on her cheeks and nose, which had been misdiagnosed as acne for 12 years. SSSB revealed multiple vellus hair bundles in funnel-shaped structures, confirming TS. Treatment with 0.025% tretinoin and 4% erythromycin gel significantly reduced the lesions, but they recurred after treatment was stopped due to pregnancy. The study suggested that TS should be considered in the differential diagnosis of treatment-resistant comedone-like lesions and that SSSB is an effective and inexpensive diagnostic method.
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