This report describes two cases where lichen planopilaris compromised hair follicles in both donor and recipient areas after follicular unit transplantation, emphasizing the need for a biopsy if lichen planopilaris is suspected.
January 2017 in “Springer eBooks” This review discusses recent advancements in hair follicle regeneration technologies, including the authors' own development of functional hair regeneration through bioengineered follicle germ transplantation, but reports no new clinical results.
June 2020 in “Applied sciences” This study introduced a semi-automatic hair follicle implanter that can reduce surgery time and fatigue for both patients and surgeons, with effectiveness demonstrated in animal and clinical trials.
May 2006 in “Dermatologic Surgery” This study found that multi-hair follicles naturally orient perpendicular to the radial line from the crown whirl, suggesting that perpendicular transplantation of grafts could replicate this natural appearance.
13 citations
,
October 2002 in “Journal of Investigative Dermatology” This study found that only one upper portion of a bisected human hair follicle successfully regenerated a complete new follicle with a pigmented hair in nude mice, although the overall success rate was very low.
6 citations
,
January 2016 in “Methods in molecular biology” This protocol describes a method for regenerating hair follicles using a bioengineering technique called the Organ Germ Method, but it reports no new clinical results.
15 citations
,
May 2004 in “Facial Plastic Surgery Clinics of North America” This article discusses follicular cell implantation as a potential solution for hair restoration limitations, but notes inconsistencies and challenges in human applications, reporting no new clinical results.
3 citations
,
May 2019 in “Medical Hypotheses” This article discusses the potential of using vitrified hair follicles from younger men with a family history of male pattern baldness to increase donor availability for future hair transplantation, and reports no clinical results.
2 citations
,
November 2022 in “Journal of Biochemistry and Molecular Biology” This review discusses how aging affects hair follicle stem cells and their environment, contributing to hair loss, and explores strategies to promote hair regrowth, but reports no new results.
August 2024 in “Cosmoderma” 3D-printed hair follicles could revolutionize hair loss treatments by providing unlimited hair grafts.
September 2017 in “Indian Journal of Plastic Surgery” This study presents an economical and user-friendly training module using common materials and goat skin to teach the steps of the strip method for hair follicle harvesting and implantation.
September 2013 in “中国医师杂志” This study found that using serum-free Williams E medium was more effective for culturing human scalp hair follicles in vitro, suggesting it may improve hair follicle regeneration between hair transplant procedures.
17 citations
,
May 2003 in “Journal of The American Academy of Dermatology” This study found that miniaturized hair follicles from pattern alopecia can regenerate rapidly when transplanted onto mice and may grow as well as or better than terminal hairs.
4 citations
,
January 2015 in “International Journal of Trichology” In this study, transplanted hair follicles from different body sites showed changes in morphology and immune status, suggesting their ability to adapt and function in new recipient areas such as the scalp or eyebrows.
7 citations
,
December 2015 in “PloS one” In this study, cryopreserved mouse whisker hair follicles were shown to maintain their hair growth potential and functional recovery, with DMSO being more effective than glycerol for cryopreservation.
7 citations
,
April 2015 in “Plastic and Aesthetic Nursing” This article reviews the causes of hair loss and explores various options for restoring the hairline, but reports no new clinical results.
April 2025 in “Journal of Cosmetic and Laser Therapy” This study found that QR678 Neo® significantly enhanced hair regrowth, density, and shaft diameter in males with advanced androgenetic alopecia undergoing hair transplant surgery, compared to a conventional method, making it a promising adjunct treatment option.
2 citations
,
April 2000 in “Plastic and Reconstructive Surgery” Dr. Vogel improved hair restoration by reducing and recycling hair plugs, achieving a more natural look and a 50-80% survival rate for replanted follicles. He emphasized understanding natural hair loss patterns, educating patients about alopecia, and refusing to operate on those who don't understand these aesthetics.
October 2015 in “Journal of Bioresource Management” This study suggests that plucked human hairs can be used to culture hair follicle cells in vitro, offering a potential, cost-effective alternative to traditional hair transplantation for treating male baldness.
November 2013 in “Journal of clinical & experimental dermatology research” This narrative review discusses the potential of urinary bladder matrix as a bio-scaffold in hair restoration but provides no new clinical results or trials; it highlights regenerative technology and suggests further exploration.
February 2024 in “Tissue & Cell” This review evaluates recent advancements in hair follicle bioengineering and discusses the potential for developing effective treatments for hair loss through tissue engineering, despite current challenges in creating functional cultured human hair cells.
39 citations
,
January 2016 in “Journal of Cutaneous and Aesthetic Surgery” This study found that intra-operative platelet-rich plasma therapy may enhance hair regrowth, increase graft density, and activate dormant follicles more effectively than normal saline in follicular unit extraction hair transplant patients.
13 citations
,
March 2012 in “The Journal of Dermatology” This study reports that transplanted mouse hair follicles restored piloerection ability and connected properly with host tissues, suggesting potential for advanced hair restoration therapies.
8 citations
,
February 2016 in “The American Journal of Dermatopathology” In this study, the researchers found that transplanted hair follicles undergo significant morphological changes, including a thickened dermal sheath and increased hair shaft diameter, which are associated with altered follicular vascularization.
8 citations
,
April 1999 in “Dermatologic Clinics” This study evaluates if using a dissecting stereomicroscope affects the rate of hair follicle transection during graft dissection, but reports no new conclusive results.
5 citations
,
September 2005 in “Dermatologic Surgery” This study reports that using LED polarized magnification in hair transplant recipient sites can reduce eye strain and improve ease of site creation, but offers no graft placement advantage over traditional methods.
4 citations
,
January 2015 in “Experimental Dermatology” This study developed a humanized scalp model in mice which demonstrated that transplanted cultured human hair follicle dermal cells contributed to the restoration of damaged hair follicles.
1 citations
,
March 2006 in “Dermatologic Surgery” This study found that using polarized magnification during hair transplant procedures may ease recipient site creation and reduce transection of existing hair follicles, potentially maximizing hair density.
April 2026 in “International Journal of Drug Delivery Technology” This review highlights the various causes and treatment options for alopecia, noting that while non-scarring types often see successful hair regrowth, scarring forms require early intervention to manage inflammatory destruction of hair follicles.
November 2023 in “International Journal of Medical Sciences” This review examines the mechanisms of hair follicle development and regeneration, discussing current hair loss treatments and emerging therapies like low-level laser therapy and stem cell therapy, which the authors suggest show promise in managing hair loss.